Results 61 to 70 of about 128,071,639 (264)
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Lower Passaic River Restoration Project & Newark Bay Study: Public Forums
, 2005 The materials were presented at public forums and were designed to provide information about the Lower Passaic River Restoration Project & Newark Bay Study and project's goals and to discuss sampling work, the dredging pilot study, and the Draft ...
core +1 more source
Insights into invasion and restoration ecology : time to collaborate towards a holistic approach to tackle biological invasions [PDF]
, 2012 The aim of our study is to provide an integrated framework for the management of alien plant invasions, combining insights and experiences from the fields of invasion and restoration ecology to enable more effective management of invasive species.
Mirijam Gaertner +14 more
core +1 more source
Meitan kexue jishuTraditional pumped hydro storage (PHS), as a mature large-scale energy storage technology, is currently constrained by factors such as terrain and land resource availability, making it increasingly challenging to meet the rapidly growing demand for ...
Zhengfu BIAN +5 more
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Клінічна хірургія, 2019 Objective. Application of the proliferative activity marker Ki-67 for analysis of the results of neoadjuvant polychemotherapy, using regional or systemic ways of delivery of pharmacological preparations, for the patients, suffering locally spread mammary
Yu. V. Dumanskiy +4 more
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Investigation of multilayer painting by means of molecular spectroscopy
EPJ Web of Conferences, 2017 The study of paintings’ layer structure under microscope was implemented in the early XX century; since that time method of cross-section preparation as well as composition of embedded materials changed and capabilities of optical microscopy broadened ...
Kadikova I.F., Grigorieva I.A.
doaj +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source