Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source
Approach to the juridical configuration of the right to housing within the Spanish legal system [PDF]
El presente artículo trata de ofrecer una visión global sobre el derecho a una vivienda digna reconocido en el ordenamiento jurídico español. Para ello se analizará no solo dónde se regula el mencionado derecho, sino también quiénes pueden ser sujetos ...
Villanueva Turnes, Alejandro
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Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Learning to Tango: Sustainable development and the multidisciplinary dream [PDF]
It is widely accepted that the creation of a sustainable future will require considerable collaboration between a range of academic and professional disciplines.
Bell, M
core
Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon +12 more
wiley +1 more source
Revisiting the self-help housing debate: Perceptions of self-help Housing by the beneficiaries of low-cost housing in South Africa [PDF]
Regardless of housing backlog and rapid urbanization created by population growth, the promotion of Self-Help Housing by authorities in charge of housing and policy documents1, there is a limited used of Self-Help Housing in South Africa.
Yengo, Andre Mengi
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ABSTRACT Objectives To evaluate the utility of cerebrospinal fluid (CSF) biomarkers—matrix metalloproteinase‐9 (MMP‐9), tissue inhibitor of metalloproteinases‐1 (TIMP‐1), the MMP‐9/TIMP‐1 ratio, and osteopontin (OPN)—as indicators of blood–brain barrier (BBB) integrity and disease activity in people with relapsing–remitting multiple sclerosis (pwMS ...
Ivan Pavlovic +6 more
wiley +1 more source
Specification Sensitivity in Right-Tailed Unit Root Testing for Explosive Behavior [PDF]
Right-tailed unit root tests have proved promising for detecting exuberance in economic and financial activities. Like left-tailed tests, the limit theory and test performance are sensitive to the null hypothesis and the model specification used in ...
Jun Yu +2 more
core
Hidden agenda in the last decade Localism and Housing Acts in the UK. Where is the good practice in East and West Midlands case studies? [PDF]
Localism acts such as Act 2011 have always accompanied and reinforced Planning Acts. For example, in Planning Act 2008, National Policy Statements describe clearly a single commissioner’s role and tasks to handle application; they also define the cases ...
Neary, Siobhan +2 more
core +1 more source
Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies
ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan +22 more
wiley +1 more source

