Results 111 to 120 of about 179,934,146 (216)

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Modeling physiological insulin sensitivity and pre-diabetic insulin resistance in multiple hPSC-derived cell types. [PDF]

Signal Transduct Target Ther
Friesen M, Jaenisch R.
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Cerebellar Perfusion Changes After Repetitive Deep Transcranial Magnetic Stimulation in Parkinson's Disease: A Five-Patient Case Series and Literature Review. [PDF]

Diagnostics (Basel)
Song IU, Chung YA, Kim BS, Na S, Park SYJ.   +4 more
europepmc   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Advanced control of chemical processes (ADCHEM '91) selected papers from the IFAC symposium, Toulouse, France, 14-16 October 1991

, 1992
This volume contains 40 papers which describe the recent developments in advanced control of chemical processes and related industries. The topics of adaptive control, model-based control and neural networks are covered by 3 survey papers.
International Federation of Automatic Control, Dufour, E., IFAC Symposium on Advanced Control of Chemical Processes <1991, Toulouse, France>, Najim, K.   +3 more
core  

A Deep-Learning-Based Scoring Framework for Large-Scale Multi-donor Cardiotoxicity Screening. [PDF]

Comput Struct Biotechnol J
Vu D, Kowalczewski A, Burnett SD, Sakolish C, Liu X, Yang H, Rusyn I, Ma Z.   +7 more
europepmc   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Intelligent control: Analytical integration of hybrid system

, 1998
This paper presents a novel approach for solving the grand challenging problem in intelligent control, i.e. the analytical and robust integration of low-level system sensing and simple control with high-level system behavior and perception.
Tarn, Tzyh Jong, Xi, Ning, Song, Mumin
core  

KaSARi: a national framework for standardized, automated, and predictive radiotherapy in Finland. [PDF]

Acta Oncol
Seppälä J, Tengström M, Korkalainen H, Virén T, Honkanen JT, Nikkinen J, Lehtiö K, Ålgars A, Keyriläinen J, Suilamo S, Nurmi H, Skyttä T, Boman E, Vatanen T, Sailas L, Arkko UM, Vuolukka K, Koivumäki T, Metsäharju T, Voivalin T, Heikkilä J.   +20 more
europepmc   +1 more source