Results 61 to 70 of about 7,296 (233)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Karstadt am Hermannplatz: Phantombild – Weichbild – Denkbild
Cahiers d’Études GermaniquesUnder the guiding concepts of phantom image, peripheral image, thought image and on the basis of Bentley’s minimal definition of theatre – “A embodies B, while C watches” – Philipp Schaefer’s department store Karstadt at Hermannplatz, opened in 1929 and ...
Kerstin HAUSBEI
doaj +1 more source
Tonel: Teaterikalitas Pascakolonial Masyarakat Tansi Sawahlunto
Jurnal Kajian Seni, 2016 Tonel is a dramatic performing arts that has been living in Tansi Society, Sawahlunto, Sumatera Barat. This study is a preliminary review of the tonel existence in the present time that related to the history of Sawahlunto as a colonialization effect ...
Dede Pramayoza
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
التراث الشعبي و المسرح تجربتان من الجزائر
إنسانيات, 2000 When one goes back to the beginning of the theatre in Algeria, one understands that investing the patrimony was an unavoidable necessity. Allalou, after the failures of Georges Abiod and Tahar Ali Chérif, use the Jeha heritage, a Thousand and One Nights,
أحمد حمومي
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Modernism, Theatricality, and Objecthood
, 2019 What I offer here may be read as a note of thanks I wrote to Michael Fried many years ago, and which I reproduce here with only minor changes. I delivered it aloud in his presence on the occasion of a panel discussion on ‘Art and Objecthood’ at the ...
Moran, Richard
core +3 more sources
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source