Results 81 to 90 of about 7,296 (233)
Ceremonial deployed with the aim of displaying and perpetuating power was a shared practice across the medieval Mediterranean. Processions, ceremonies, and ritual acts created solidarity and consensus, naturalized dominion, and conveyed legitimacy while ...
Karen Rose Mathews
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
"This collection of essays explores the changing connotations of "theatricality" for theatrical performance and everyday life. Six case studies, each written by a specialist in the field, use historically specific circumstances to illustrate how ...
Postlewait, Thomas(viaf)2492050 +1 more
core
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
This article is the result of practical research in the field of performing arts, with emphasis on processes and artistic achievements in studies focused in Pirandello’s scene studies.
Martha de Mello
doaj
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
"The original essays in Oxford Twenty-First Century Approaches to Literature mean to provoke rather than reassure, to challenge rather than codify. Instead of summarizing existing knowledge scholars working in the field aim at opening fresh discussion ...
Turner, Henry S.,edt
core +2 more sources
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Teaching English following learner-based model
When Russia entered international education space, it caused the necessity to analyse the most important spheres in the field of students’ professional training and it had to change the format of education in the humanities, which has to be in line with ...
Elena G. Kashina, Tatjana I. Rudneva
doaj

