Results 211 to 220 of about 3,781 (264)

Conversion of thebaine to codeine

Journal of Medicinal Chemistry, 1976
An improved conversion of thebaine to codeine has been developed. Oxymercuration of thebaine with mercuric acetate in refluxing methanol, followed by hydrolysis of the intermediate 7-acetomercurineopinone dimethyl ketal with 3 N acetic acid, or, alternatively, reduction of the organomercury compound with sodium borohydride and mild acid hydrolysis of ...
R B, Barber, H, Rapoport
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ChemInform Abstract: THEBAINE AND ACETYLENIC DIENOPHILES

Chemischer Informationsdienst, 1982
AbstractThebain (1) reagiert mit Propiolsäuremethylester (II) in Methanol zu den beiden Addukten(I1I) und (IV).
A. SINGH, S. ARCHER, K. HOOGSTEEN, J. HIRSHFIELD   +3 more
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Acyl‐normethine aus Thebain

Chemische Berichte, 1967
AbstractBei der Öffnung des Piperidinringes im Thebain mit Acetyl‐ und Benzoylchlorid sowie Chlorameisensäure‐äthyl‐und ‐benzylester in feuchtem Äthylacetat entstehen die entsprechen‐den Codeinon‐acyl‐normethine (1a–1d), die je nach Katalyse interessante Umlagerungs‐und Spaltungsreaktionen eingehen.
Christa Bertgen, Wilhelm Fleischhacker, Franz Vieböck   +2 more
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Mikrobielle Umwandlung von Thebain

Experientia, 1969
Thebaine was transformed into 2 products by fermentation with a strain ofTrametes cinnabarina. The 2 compounds were isolated and identified as 14-Β-hydroxycodeinone and 14-Β-hydroxycodeinone-N-oxid.
D. Gröger, H. P. Schmauder
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Determination of thebaine in crude thebaine samples by infrared and ultraviolet spectrophotometric methods

The Analyst, 1984
The determination of the thebaine content of crude thebaine concentrates by infrared and ultraviolet spectrophotometric methods is described. The results obtained with the two methods were found to compare favourably. The accuracy of these procedures was found to be superior to that of the K–34 (U.N.) method.
Arun Agnihotri, Satish Chandra Tewari, Pavan Khatod, Sadhana Banerjee, M. Balasubramanian   +4 more
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Structural insights into thebaine synthase 2 catalysis

Biochemical and Biophysical Research Communications, 2020
Thebaine synthase 2 (THS2) that can transform (7S)-salutaridinol 7-O-acetate to thebaine catalyzes the final step of thebaine biosynthesis in Papaver somniferum. Here, the crystal structures of THS2 and its complex with thebaine are reported, revealing the interaction network in the substrate-binding pocket.
Chun-Chi Chen, Jing Xue, Wei Peng, Binju Wang, Lilan Zhang, Weidong Liu, Tzu-Ping Ko, Jian-Wen Huang, Shuyu Zhou, Jian Min, Lixin Ma, Longhai Dai, Rey-Ting Guo, Xuejing Yu   +13 more
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Thebaine Adducts with Maleimides. Synthesis and Transformations.

ChemInform, 2005
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
E.E. Shults, M.M. Shakirov, G.A. Tolstikov, V.N. Kalinin, G. Schmidhammer   +4 more
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Über das β‐Dihydro‐thebain

Helvetica Chimica Acta, 1950
AbstractThebain wird durch LiAlH4 in ein Dihydro‐thebain (β‐Dihydrothebain, VI) übergeführt, dessen Konstitution ermittelt worden ist. Die Verbindung ist stereoisomer mit dem schon bekannten „Thebainon‐enol‐methyläther”︁ (V) und unterscheidet sich von diesem durch Konfigurationsänderung am C‐Atom 14.
H. Schmid, P. Karrer
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Thebaine from Root Cultures of Papaver bracteatum

Planta Medica, 1982
Root cultures derived from cell suspension cultures of Papaver bracteatum were shown to produce thebaine (yield 0.03%).
S W, Zito, E J, Staba
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Cyclo-adducts of thebaine with nitrosoarenes

Journal of the Chemical Society, Perkin Transactions 1, 1979
Thebaine (1) reacts reversibly with various nitroso-arenes to form cyclo-adducts by 1,4-addition of the nitrosogroup to the conjugated diene system of the alkaloid. Adducts (2) of thebaine with nitrosobenzene and with 4-chloro-, 4-methyl-, 3-methoxy-, and 4-nitro-nitrosobenzene have been prepared in good yield.
Gordon W. Kirby, Kenneth W. Bentley, Peter Horsewood, Serjinder Singh   +3 more
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