Results 161 to 170 of about 1,039,047 (309)

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Models of Care for Mental Health Nurse Practitioners in Emergency Department Settings: A Scoping Review Across High-Income Countries. [PDF]

Int J Ment Health Nurs
Manzoor N, Maude P, Ross A.
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

'Let's Just Hope for the Best': A Photovoice Study Exploring the Impact of Covid-19 Restrictions on Children With Intellectual Disabilities in the UK. [PDF]

J Appl Res Intellect Disabil
Mair APA, Khawam G, Christie H, Goodall K, McConachie D, Van Herwegen J, Moss J, Ballantyne C, Crawford H, Richards C, Gallagher-Mitchell T, Outhwaite L, Gillespie-Smith K.   +12 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

The application of tins to enhance theme-based inquiry learning in a taiwanese rural elementary school.

, 2010
此乃國科會專題計畫所產生的論文，計畫編號：NSC-92-2511-S-026-001[[abstract]]The purpose of this study was to apply a theme-based inquiry network studio (abbreviated as TINS) to conduct a theme-based inquiry learning under a theme Nano technology.
許銘津, Lin, M.J.;Lin, C. D.
core  

Evolving aspects of oral care in older adults: a systematic review and Meta-synthesis. [PDF]

BMC Oral Health
Neshati A, Farzaie Ardejanie N, Naeimi S, Pashmforosh M, Askari Z, Rafi A.   +5 more
europepmc   +1 more source

Oligonucleotide Theme

European Journal of Pharmaceutical Sciences, 2000
openaire   +2 more sources

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Marketing features of derived intoxicating cannabinoid product brands on Instagram: A content analysis. [PDF]

Addiction
La Capria K, Meng S, Padon AA, Tillett KK, Donaldson SI, Allem JP, Rossheim ME, LoParco C, Berg CJ, Jackson KM, Chen-Sankey J.   +10 more
europepmc   +1 more source