Results 161 to 170 of about 8,099 (198)

Neuer Abbau des Theobromins

Berichte der deutschen chemischen Gesellschaft, 1897
Ahnlich dem Caffein und dem Xanthin wird das Theobromin durch Salzsaure und Kaliumchlorat, wie der eine von uns vor langerer Zeit gezeigt hat, zum groseren Teil in Monomethylalloxan und Monomethylharnstoff gespalten1). Andererseits erhalt man aus dem Caffein bei Ausschlus von Wasser, z. B.
Emil Fischer, Fritz Frank
openaire   +1 more source

New theobromine derivative as apoptotic anti-triple-negative breast cancer targeting EGFR protein: CADD story

Journal of Molecular Structure, 2023
I. Eissa, Reda G. Yousef, Hazem Elkady, E. Elkaeed, Dalal Z. Husein, Ibrahim M. Ibrahim, B. Alsfouk, A. Doghish, Hesham A. El-Mahdy, A. Kenawy, N. El-Deeb, A. Metwaly   +11 more
semanticscholar   +1 more source

New Antihistaminic Theophylline or Theobromine Derivatives

Journal of Medicinal Chemistry, 1985
A series of 3,4-dihydro-1,3-dimethyl-7-[3-(4-substituted-piperazin-1-yl)- substituted-alkyl]-1H-purine-2,6-diones and 3,7-dihydro-3,7-dimethyl-1-[3-(4-substituted-piperazin-1-yl)- substituted-alkyl]-1H-purine-2,6-diones was synthesized and evaluated for antihistaminic activity.
J C, Pascal, S, Beranger, H, Pinhas, A, Poizot, J P, Désiles   +4 more
openaire   +2 more sources

Design, semi-synthesis, anti-cancer assessment, docking, MD simulation, and DFT studies of novel theobromine-based derivatives as VEGFR-2 inhibitors and apoptosis inducers

Comput. Biol. Chem., 2023
I. Eissa, Reda G. Yousef, Hazem Elkady, E. Elkaeed, Aisha A. Alsfouk, Dalal Z. Husein, Ibrahim M. Ibrahim, Mostafa A. Elhendawy, Murrell Godfrey, A. Metwaly   +9 more
semanticscholar   +1 more source

Correlation between dietary theobromine intake and low cognitive performance in older adults in the United States: A cross-sectional study based on the National Health and Nutrition Examination Survey.

Asia Pacific Journal of Clinical Nutrition, 2023
Longzhu Zhao, Runqing Zhan, Xueting Wang, Ruihan Song, Miaomiao Han, Xiaoli Shen   +5 more
semanticscholar   +1 more source

Interaction of Theobromine with Sodium Benzoate

Journal of Pharmaceutical Sciences, 1982
The interaction of theobromine with sodium benzoate was investigated by PMR spectroscopy. The interaction of theobromine with pentadeuterated benzoic acid (benzoic acid-d5) was examined in the same manner but to a lesser degree. Chemical shifts of theobromine protons were determined as a function of sodium benzoate concentration in deuterium oxide at ...
J, Nishijo, I, Yonetani
openaire   +2 more sources

Neuroprotective Effects of Theobromine in permanent bilateral common carotid artery occlusion rat model of cerebral hypoperfusion

Metabolic brain disease, 2022
J. Bhat, Manish Kumar
semanticscholar   +1 more source

Simultaneous determination of theobromine, theophylline, and caffeine using a modified electrode with petal-like MnO2 nanostructure.

Talanta: The International Journal of Pure and Applied Analytical Chemistry, 2021
Nasrin Arefi Nia, M. Foroughi, S. Jahani
semanticscholar   +1 more source

Theobromine and the Pharmacology of Cocoa

2010
The effects of theobromine in man are underresearched, possibly owing to the assumption that it is behaviourally inert. Toxicology research in animals may appear to provide alarming results, but these cannot be extrapolated to humans for a number of reasons. Domestic animals and animals used for racing competitions need to be guarded from chocolate and
openaire   +2 more sources

Neuroprotective effects of theobromine in transient global cerebral ischemia-reperfusion rat model.

Biochemical and Biophysical Research Communications - BBRC, 2021
J. Bhat, Sushma Gupta, M. Nireekshan Kumar   +2 more
semanticscholar   +1 more source