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The Potential of Microwave Radiation and Mechanochemistry in the Formation of Purine Alkaloids Cocrystals Using Pyromellitic Acid as a Coformer: Synthesis, Structural, Spectroscopic, Thermal Analysis, and Biological Properties. [PDF]
Cryst Growth DesCal W +6 more
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The Impact of Controlled Fermentation Temperature on Chemical Composition and Sensory Properties of Cacao. [PDF]
FoodsCalvo AM +5 more
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Mutation Research/Reviews in Genetic Toxicology, 1975
Theobromine and theophylline have a limited therapeutic use and in addition they occur in plants used in the preparation of a number of widely consumed drinks. Thus most of the population must be exposed to both compounds. Chromosome abnormalities are caused by both theobromine and theophylline in plant cells and in mammalian cells in culture, and both
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Theobromine and theophylline have a limited therapeutic use and in addition they occur in plants used in the preparation of a number of widely consumed drinks. Thus most of the population must be exposed to both compounds. Chromosome abnormalities are caused by both theobromine and theophylline in plant cells and in mammalian cells in culture, and both
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Determination of theobromine in theobromine and sodium salicylate
Journal of the American Pharmaceutical Association (Scientific ed.), 1949A volumetric, acidimetric method is proposed as a substitute for the present N. F. gravimetric method. The proposed method features several advantages such as, ease of operation, saving of time, elimination of an empiric correction factor, and a high degree of precision and accuracy. Results are submitted to show that the present N. F.
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Theobromine kinetics and metabolic disposition
Clinical Pharmacology and Therapeutics, 1983Metabolism and kinetics of a single oral dose of 30 microCi 8-14C-theobromine with 10 mg/kg theobromine sodium acetate were studied in six healthy, nonmedicated, nonsmoking men after 14 days' abstention from all methylxanthine sources. Identification and quantitation of metabolites in plasma and urine both by HPLC and by thin-layer chromatography ...
S M, Tarka +3 more
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Theobromine metabolism in man.
Drug Metabolism and Disposition, 1982The effects of allopurinol on the plasma clearance and metabolism of theobromine have been investigated under multiple-dosing conditions. Allopurinol had no effect on the clearance of theobromine, indicating that the elimination of this compound is dependent on enzyme systems other than xanthine oxidase, presumably the hepatic mixed-function oxidases ...
J O, Miners, J, Attwood, D J, Birkett
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Methylxanthines. II. Anhydrous Theobromine
Acta Crystallographica Section C Crystal Structure Communications, 1998Clear crystals of anhydrous theobromine (3,7-dihydro-3,7-dimethyl-1H-purine-2,6-dione, C7H8N4O2) were grown by vacuum sublimation and the X-ray structure determined. The melting point of anhydrous theobromine has been determined as 620 (1) K. Two molecules in the asymmetric unit form a pseudo- centrosymmetric dimer and pack to form a layered structure ...
K. A. Ford, Y. Ebisuzaki, P. D. Boyle
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