Results 91 to 100 of about 85,619 (248)
Experimental rat models of chronic allograft nephropathy: a review [PDF]
, 2014 Chronic allograft nephropathy (CAN) is the leading cause of late allograft loss after renal transplantation (RT), which continues to remain an unresolved problem. A rat model of CAN was first described in 1969 by White et al. Although the rat model of RT
Haylor, John, Shrestha, Badri
core +2 more sources
Elevated Salivary Theobromine and Long‐Term Improvement of Periodontal Health in Two Cohort Studies
Journal of Clinical Periodontology, Volume 53, Issue 3, Page 445-454, March 2026.ABSTRACT Background Theobromine, a methylxanthine mainly found in chocolate, has been suggested to possess various health‐promoting properties. This study aimed to investigate the long‐term effect of salivary theobromine levels on periodontitis severity using 7‐ and 10‐year follow‐up data from the prospective Studies of Health in Pomerania (SHIP‐TREND ...
Thomas Kocher +8 more
wiley +1 more source
Gram‐Scale Synthesis of an Arylsulfonamide‐Type Alkaline Phosphatase Inhibitor
ChemMedChem, Volume 21, Issue 4, 25 February 2026.A larger amount of a tissue‐nonspecific alkaline phosphatase inhibitor, 5‐((5‐chloro‐2‐methoxyphenyl)sulfonamido)nicotinamide, was synthesized in five steps using a parallel method without the need for chromatography or crystallization. Because a single batch was used for in vivo studies in a large population of mice, the pharmacological results were ...
Zsolt Rapi +2 more
wiley +1 more source
The Old Friend Ruthless Enemy - Theophylline Toxicity: A Case Report
Journal of Pediatric Emergency and Intensive Care Medicine, 2020 Theophylline is an old drug of modern medicine. Theophylline toxicity may develop both with acute or chronic intakes due to its narrow therapeutic index.
Hasan Serdar Kıhtır +5 more
doaj +1 more source
Theophylline inhibits the cough reflex through a novel mechanism of action☆
Journal of Allergy and Clinical Immunology, 2014 Background Theophylline has been used in the treatment of asthma and chronic obstructive pulmonary disease for more than 80 years. In addition to bronchodilator and anti-inflammatory activity, clinical studies have suggested that theophylline acts as an ...
E. Dubuis +6 more
semanticscholar +1 more source
Disparate effects of chronic and acute theophylline on cyclosporine A nephrotoxicity [PDF]
, 2018 : We previously developed a model of acute cyclosporine A (CsA)-induced vasomotor nephrotoxicity in rabbits. As exogenous adenosine infusion mimics the haemodynamic changes that characterize acute renal failure (ARF), we wanted to know whether adenosine ...
Gouyon, Jean-Bernard +5 more
core
Diagnosis, evaluation, and management of acute kidney injury : a KDIGO summary (part 1) [PDF]
, 2013 Acute kidney injury (AKI) is a common and serious problem affecting millions and causing death and disability for many. In 2012, Kidney Disease: Improving Global Outcomes completed the first ever, international, multidisciplinary, clinical practice ...
Kellum, John A, Lameire, Norbert
core +3 more sources
Journal of Science: Advanced Materials and Devices, 2019 This paper describes a selective and sensitive detection of bronchodilators (theophylline) using an aloe vera plant extract decorated iron tungstate nanorods (AFW) immobilized Nafion (Nf) modified glassy carbon electrode (GCE) (AFW/Nf/GCE).
A. Karthika +3 more
doaj +1 more source
Theophylline and silymarin are potent inhibitors of IL-4 secretion from activated human basophils
American Journal of Experimental and Clinical Research, 2018 Basophils are the most important cells in allergic reactions and secret interleukin 4 (IL-4) and tumor necrosis factor α (TNFα) mediators. Theophylline as a phosphodiesterase 4 inhibitor and silymarin with its anti-inflammatory effects seem to be useful ...
Hamidreza Jahanbani-Ardakani +4 more
doaj
Standard Error of Empirical Bayes Estimate in NONMEM® VI. [PDF]
, 2012 The pharmacokinetics/pharmacodynamics analysis software NONMEM® output provides model parameter estimates and associated standard errors. However, the standard error of empirical Bayes estimates of inter-subject variability is not available. A simple and
Bae, Kyun-Seop +4 more
core +2 more sources