Results 51 to 60 of about 24,868 (197)

SIADH and Hyponatremia with Theophylline

open access: yesThe Annals of Pharmacotherapy, 2002
OBJECTIVE: To report a case of possible theophylline-induced hyponatremia due to the syndrome of inappropriate antidiuretic hormone (SIADH). CASE SUMMARY: An 88-year-old man developed severe symptomatic hyponatremia (serum sodium 112 ...
Liberopoulos, E. N.   +3 more
openaire   +3 more sources

Understanding the Molecular Processes of Obesity and the Anti‐Obesity Properties of Bioactive Substances Found in Tea

open access: yesPhytochemicals in Food and Medicine, Volume 1, Issue 3, September 2026.
ABSTRACT Obesity, a severe worldwide health concern, is characterized as an excessive deposit of fat in the human body. It has various ramifications that endanger human health and increase the financial expense. Obesity raises the risk of several illnesses, notably cardiovascular disease, NALFD, and diabetes, and has been associated with shorter ...
Sakhawat Riaz   +6 more
wiley   +1 more source

Current status and usefulness of therapeutic drug monitoring implementation of theophylline in elderly patients based on a nationwide database study and modeling approach

open access: yesScience Progress
Objectives: Theophylline is used in the treatment of chronic obstructive pulmonary disease but readily causes symptoms of intoxication and exhibits high risks in elderly patients.
Akira Okada   +4 more
doaj   +1 more source

The Development and Validation of a Simple Method for the Determination of Meropenem Concentrations in Human Plasma Using High‐Performance Liquid Chromatography

open access: yesApplied Research, Volume 5, Issue 4, August 2026.
A simple, rapid, and sustainable HPLC‐UV method was developed and validated to quantify meropenem in human plasma across a wide linear range (0.5–100 mg/L). Utilizing an efficient one‐step protein precipitation, this eco‐friendly approach is highly suited for routine clinical therapeutic drug monitoring and research purposes.
Asma Aboelezz   +2 more
wiley   +1 more source

Quantitative prediction of intravenous drug interactions caused by cytochromes P450 inhibitors and inducers

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2682-2692, August 2026.
Background Aims Pharmacokinetic interaction studies typically focus on oral administration, but intravenous (IV) administration bypasses intestinal degradation and hepatic first‐pass metabolism, leading to distinct drug–drug interaction (DDI) magnitude. This study aimed to develop a predictive model for DDIs involving IV‐administered drugs.
Vianney Tuloup   +2 more
wiley   +1 more source

Efficacy and side effects of intravenous theophylline in acute asthma: a systematic review and meta-analysis

open access: yesDrug Design, Development and Therapy, 2018
Gulixian Mahemuti, Hui Zhang, Jing Li, Nueramina Tieliwaerdi, Lili Ren Respiratory Department, The Second Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang Province, People’s Republic of China Background and objective ...
Mahemuti G   +4 more
doaj  

DIMETILSULFOKSID SEBAGAI ENHANCER TRANSPOR TRANSDERMAL TEOFILIN SEDIAAN GEL

open access: yesPharmaciana, 2013
Dimethylsulfoxide (DMSO) has been intensively studied the 19th century. This substance is used as a medicine and solve. It can also be used as an absorption enhancer of various drugs, either synthetical or herbal medicines.
Resty Annisa Damayanti, Tedjo Yuwono
doaj   +1 more source

Physiologically‐based pharmacokinetic modelling of uridine 5′‐diphosphoglucorosultransferase (UGT) substrate drugs in pregnant women

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2764-2776, August 2026.
Aims While pregnancy‐related changes in phase I enzyme activity are well‐documented, less is known about the impact on phase II enzymes. This study aimed to test the hypothesis that changes in the pharmacokinetics (PK) of uridine 5′‐diphosphoglucuronosyltransferase (UGT) substrates during pregnancy result from altered enzyme expression or activity ...
William Saffaf   +6 more
wiley   +1 more source

Kinetic study of peroxidase enzyme in the presence of purine alkaloids

open access: yesیافته‌های نوین در علوم زیستی, 2022
Peroxidase catalyzes different oxidation of substrates using hydrogen peroxide, a reactive oxygen specie (ROS). ROS, at low concentrations, act as messenger to regulate intracellular signaling, whereas, at high concentrations, they can overcome the ...
Tayyebeh Rahmati darvazi   +1 more
doaj  

Cord Blood Theophylline Levels and Respiratory Morbidities In Preterm Infants

open access: yesGynecology Obstetrics & Reproductive Medicine, 2019
Objective: to investigate whether there is any relationship between cord blood theophylline levels and pulmonary morbidities in the early neonatal period in premature infants.
Tolga Hasan Celik   +3 more
doaj   +1 more source

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