Results 51 to 60 of about 55,199 (226)

Predictive Factors for Efficacy and Safety of Prophylactic Theophylline for Extubation in Infants with Apnea of Prematurity.

PLoS ONE, 2016
PurposeThis study aimed to evaluate predictive factors involved in efficacy and safety in Japanese infants who received theophylline therapy to prevent apnea of prematurity (AOP) after weaning from mechanical ventilation.MethodsWe retrospectively ...
Tomoko Kondo, Yuki Kondo, Yuji Orita, Fumi Mitarai, Yoichi Ishitsuka, Mitsuru Irikura, Yoshihiro Shimodozono, Tsutomu Douchi, Yasuo Takeda, Tetsumi Irie   +9 more
doaj   +1 more source

Solubility and thermodynamic properties of sodium theophylline salt in aqueous sodium hydroxide solution at different temperatures

Journal of Chemical Research, 2023
The solubility data of sodium theophylline salt in the water and aqueous sodium hydroxide systems with molarities of 0.00, 0.01, 0.10, 0.20, 0.49, and 0.96 mol kg −1 at temperatures ranging from 283.15 to 368.15 K are determined via the equilibrium ...
Zhenhuan Dong, Lingqi Kong, Zhen Liu, Anming Yang   +3 more
doaj   +1 more source

Clustering in Additive Mixed Models with Approximate Dirichlet Process Mixtures using the EM Algorithm [PDF]

, 2013
We consider additive mixed models for longitudinal data with a nonlinear time trend. As random effects distribution an approximate Dirichlet process mixture is proposed that is based on the truncated version of the stick breaking presentation of the ...
Heinzl, Felix, Tutz, Gerhard
core   +2 more sources

Endogenous melatonin partial metabolic clearance as a potential endogenous marker of CYP1A2 activity

British Journal of Clinical Pharmacology, EarlyView.
Aims Cytochrome P450 1A2 (CYP1A2) exhibits substantial interindividual variability, necessitating appropriate phenotyping strategies for personalized pharmacotherapy. This study evaluated endogenous melatonin partial metabolic clearance (CLm(MEL)), calculated from urinary 6‐hydroxymelatonin (6‐O‐MEL) excretion and plasma melatonin (MEL) exposure, as a ...
Akitomo Yokokawa, Hayato Shimazaki, Shunji Igarashi, Yoshiki Tagawa, Naoki Hisada, Hiromi Shibasaki   +5 more
wiley   +1 more source

Evaluation of theophylline therapeutic drug monitoring service

Zdravniški Vestnik, 2015
BackgroundTherapeutic monitoring of theophylline serum levels is required due to its narrow therapeutic range and marked interindividual pharmacokinetic variability.
Neža Rugelj, Katja Čvan Trobec, Mitja Pišlar, Pika Meško Brguljan, Mitja Košnik, Aleš Mrhar   +5 more
doaj  

Theophylline versus NSAID in the Treatment of Postdural Puncture  Headache in Obstetric Patients

Pakistan Armed Forces Medical Journal
Objective: To determine the effectiveness of oral Theophylline compared to Non-Steroidal Anti-Inflammatory Drugs in the management of postdural puncture headache in obstetric patients. Study Design: Quasi-experimental Study.
Tariq Mehmood, Rao Ali Shan Khan, Muhammad Awais Qarni, Kaukab Majeed Kayani, Usman Khalid, Hina Iftikhar   +5 more
doaj   +1 more source

Therapeutic and toxic blood concentrations of nearly 1,000 drugs and other xenobiotics [PDF]

, 2012
Introduction: In order to assess the significance of drug levels measured in intensive care medicine, clinical and forensic toxicology, as well as for therapeutic drug monitoring, it is essential that a comprehensive collection of data is readily ...
Andresen, Hilke, Iwersen-Bergmann, Stefanie, Schmoldt, Achim, Schulz, Martin   +3 more
core   +1 more source

Anti‐Obesity Pharmacotherapy and Emerging Multimodal Interventions for Obstructive Sleep Apnea

Chronic Diseases and Translational Medicine, EarlyView.
Cellular and molecular mechanisms of obesity‐related obstructive sleep apnea (OSA). ADMA: asymmetric dimethyrarginine, NLRP3: nucleotide‐binding domain, leucine‐rich repeat family, Pyrin domain containing 3, TLR: toll‐like receptors, IL‐1β: interleukin‐1β, IL‐6: interleukin‐6; LPS: lipopolysacharide, ROS: reactive oxygen species, TNF‐α.
Anish Preshy, Cornelius J. Fernandez, Mohammad Hamid Nedai, Joseph M. Pappachan   +3 more
wiley   +1 more source

Theophylline Use to Prevent Permanent Pacing in the Contemporary Era of Heart Transplantation: The Rotterdam Experience

Frontiers in Cardiovascular Medicine, 2022
IntroductionSinus node dysfunction and atrioventricular conduction disorders occur increasingly after orthotopic heart transplantation (HTX) due to aging donors and may require permanent pacemaker (PM) implantation. Theophylline has been used in the past
Claudette Kooij, Tamas Szili-Torok, Stefan Roest, Stefan Roest, Alina A. Constantinescu, Alina A. Constantinescu, Jasper J. Brugts, Jasper J. Brugts, Olivier Manintveld, Olivier Manintveld, Kadir Caliskan, Kadir Caliskan   +11 more
doaj   +1 more source

Effect of Theophylline as Adjunct to Inhaled Corticosteroids on Exacerbations in Patients With COPD: A Randomized Clinical Trial [PDF]

, 2018
Importance: Chronic obstructive pulmonary disease (COPD) is a major global health issue and theophylline is used extensively. Preclinical investigations have demonstrated that low plasma concentrations (1-5 mg/L) of theophylline enhance antiinflammatory ...
Barnes, Peter J., Briggs, Andrew, Burns, Graham, Chaudhuri, Rekha, Chrystyn, Henry, Cotton, Seonaidh, Davies, Lisa, De Soyza (Newcastle), Anthony, Devereux, Graham, Fielding, Shona, Gompertz, Simon, Haughney, John, Innes, Karen, Kaniewska, Joanna, Lee, Amanda, McMeekin, Nicola, Morice, Alyn, Norrie, John, Price, David, Sullivan, Anita, Wilson, Andrew   +20 more
core   +2 more sources