Results 51 to 60 of about 1,116,546 (296)

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Artificial Intellignce: Art or Science? [PDF]

open access: yes, 1988
Computer programs are new kinds of machines with great potential for improving the quality of life. In particular, expert systems could improve the ability of the small, weak and poor members of society to access the information they need to solve their ...
Bundy, Alan
core   +1 more source

Unsharp Values, Domains and Topoi [PDF]

open access: yes, 2011
The so-called topos approach provides a radical reformulation of quantum theory. Structurally, quantum theory in the topos formulation is very similar to classical physics.
Barbosa, Rui Soares, Doering, Andreas
core   +1 more source

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani   +10 more
wiley   +1 more source

Editorial:  Applied Computing 2023

open access: yesمجلة بغداد للعلوم
Applied computing utilizes aspects of computer science to solve problems in several disciplines, including business, politics, education, and the environment.
Yousra Abdul Alsahib S. Aldeen   +2 more
doaj   +1 more source

Interactive game as a means of developing extracurricular activities in informatics

open access: yesRUDN Journal of Informatization in Education, 2019
Problem and goal. The article describes the processes of development of methods of teaching computer science in the organization of extracurricular activities, which contributes to the effectiveness of teaching computer science through the use of games ...
Olga Yu. Zaslavskaya
doaj   +1 more source

Epistemic and social scripts in computer-supported collaborative learning [PDF]

open access: yes, 2005
Collaborative learning in computer-supported learning environments typically means that learners work on tasks together, discussing their individual perspectives via text-based media or videoconferencing, and consequently acquire knowledge. Collaborative
A. Geyken   +42 more
core   +6 more sources

Effects of Causal Beliefs About Gout on Public Views About Gout Management: A Randomized Experimental Study

open access: yesArthritis Care &Research, EarlyView.
Objective Despite well‐described biologic causes, the public views unhealthy lifestyle choices as the primary cause of gout. This study investigated how causal beliefs about gout influence the public's views about its management. Methods In a randomized study, 201 members of the public viewed one of two 2‐minute videos about gout.
Rachel Murdoch   +6 more
wiley   +1 more source

THE MODAL µ-CALCULUS: A SURVEY

open access: yesTASK Quarterly, 2005
The modal µ-calculus is an extension of modal logic with two operators µ and ν, which give the least and greatest fixpoints of monotone operators on powersets.
GIACOMO LENZI
doaj  

Obesity subtypes and longitudinal trajectories of function over 7‐years of follow‐up: data from the Multicenter Osteoarthritis Study

open access: yesArthritis Care &Research, Accepted Article.
Background Obesity, defined by BMI ≥30kg/m2, is a risk factor for functional limitations in people with knee osteoarthritis (OA). However, function varies among such individuals. Our objective was to evaluate the implications of obesity subtypes on longitudinal patterns of physical functioning in people with or at risk for knee OA.
Kristine Godziuk   +6 more
wiley   +1 more source

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