Results 51 to 60 of about 1,693,747 (308)
On the practically interesting instances of MAXCUT [PDF]
, 2012 The complexity of a computational problem is traditionally quantified based on the hardness of its worst case. This approach has many advantages and has led to a deep and beautiful theory.
Bilu, Yonatan +3 more
core +6 more sources
A stepwise emergence of evolution in the RNA world
FEBS Letters, EarlyView.How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation
FEBS Letters, EarlyView.The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt +8 more
wiley +1 more source
FEBS Letters, EarlyView.In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi +5 more
wiley +1 more source
Фізико-математична освіта, 2021 Relevance and expediency of introduction of a training course of computer mathematics for students of “Secondary Education (Computer Science)” is caused by necessity of use of computer equipment with the corresponding software almost in all areas of ...
Варвара Черненко
doaj +1 more source
FEBS Letters, EarlyView.This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter +8 more
wiley +1 more source
Input Redundancy for Parameterized Quantum Circuits
Frontiers in Physics, 2020 One proposal to utilize near-term quantum computers for machine learning are Parameterized Quantum Circuits (PQCs). There, input is encoded in a quantum state, parameter-dependent unitary evolution is applied, and ultimately an observable is measured. In
Francisco Javier Gil Vidal +2 more
doaj +1 more source
The Era of Big Data Comes to Oceanography [PDF]
Oceanography, 2013 The late Jim Gray, who received the prestigious Turing Award in computer science and was a pioneer in the development of relational databases, proposed the "Fourth Paradigm" to describe the field of data-intensive science (Hey et al., 2009).
Mark R. Abbott
doaj +1 more source
Revista Brasileira de Ensino de Ciência e Tecnologia, 2021 This paper aims to understand the didactic formation of teachers/professors in IT and Computer Science from campus Colinas do Tocantins, of the Tocantins Federal Institute for Education, Science and Technology (IFTO).
Eliane Mittelstad Martins de Souza +3 more
doaj +1 more source
Quantum Applications In Political Science [PDF]
, 2020 Undergraduate Research ScholarshipThis paper will show the current state of quantum computation and its application as a political science research method.
Costa, Caleb
core