Results 41 to 50 of about 667,753 (295)
Dendritic cells steering antigen and leukocyte traffic in lymph nodes
FEBS Letters, EarlyView.Dendritic cells are key players in the activation of T cells and their commitment to effector function. In this In a Nutshell Review, we will discuss how dendritic cells guide the trafficking of antigen and leukocytes in the lymph node, thus influencing T‐cell activation processes. Dendritic cells (DCs) play a central role in initiating and shaping the
Enrico Dotta +3 more
wiley +1 more source
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Synthetic Symbiosis under Environmental Disturbances
mSystems, 2020 By virtue of complex ecologies, the behavior of mutualisms is challenging to study and nearly impossible to predict. However, laboratory engineered mutualistic systems facilitate a better understanding of their bare essentials.
Jai A. Denton, Chaitanya S. Gokhale
doaj +3 more sources
Frontiers in Neuroscience, 2018 Purpose: To present a new modified tri-exponential model for diffusion-weighted imaging (DWI) to detect the strictly diffusion-limited compartment, and to compare it with the conventional bi- and tri-exponential models.Methods: Multi-b-value diffusion ...
Qiang Zeng +5 more
doaj +1 more source
A stepwise emergence of evolution in the RNA world
FEBS Letters, EarlyView.How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
THEORETICAL MODELS OF DARK ENERGY [PDF]
International Journal of Modern Physics D, 2012 Mounting observational data confirm that about 73% of the energy density consists of dark energy which is responsible for the current accelerated expansion of the Universe. We present observational evidences and dark energy projects. We then review various theoretical ideas that have been proposed to explain the origin of dark energy; they contain the ...
Yuki Watanabe, Jaewon Yoo
openaire +4 more sources
Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation
FEBS Letters, EarlyView.The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt +8 more
wiley +1 more source
Brazilian Journal of Psychiatry, 1999 A compreensão da experiência dissociativa e das origens dos transtornos dissociativos é difícil devido à complexidade da questão. As contradições da classificação são decorrentes das dificuldades de se construir uma teoria da mente abrangente que ...
Paulo Jacomo Negro Junior +2 more
doaj +1 more source
Renormalization: A Number Theoretical Model [PDF]
Communications in Mathematical Physics, 2007 We analyse the Dirichlet convolution ring of arithmetic number theoretic functions. It turns out to fail to be a Hopf algebra on the diagonal, due to the lack of complete multiplicativity of the product and coproduct. A related Hopf algebra can be established, which however overcounts the diagonal.
openaire +3 more sources
FEBS Letters, EarlyView.In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi +5 more
wiley +1 more source