Results 131 to 140 of about 5,869 (242)

Light‐Controlled Modulation of 15‐Lipoxygenase‐1 Regulates Intestinal Inflammatory Signaling

open access: yesAngewandte Chemie, EarlyView.
The developed target‐guided strategy enables the rational design of diazo‐based photoswitchable inhibitors of 15‐lipoxygenase‐1. Distinct molecular architectures program opposite light‐dependent activity, allowing on‐demand control of enzyme inhibition.
Anastasia Louka   +10 more
wiley   +2 more sources

Protonation‐Gated Orthogonal Control of Highly Efficient Molecular Motors With Broad Visible‐Light Responsiveness

open access: yesAngewandte Chemie, EarlyView.
Reversible protonation gates coumarin‐based overcrowded‐alkene molecular motors by dynamically reshaping their conjugation topology. This strategy enables efficient, near‐quantitative unidirectional photoisomerization from blue–green to red‐shifted visible light up to 600 nm, while preserving motor function and allowing orthogonal light, heat, and acid/
Jinghao Wang   +2 more
wiley   +2 more sources

Generation of the Camptothecin Scaffold by a Flavin‐Catalyzed Photooxidative Skeletal Reorganization

open access: yesAngewandte Chemie, EarlyView.
The biosynthetic pathway of the anticancer drug precursor camptothecin involves an enigmatic skeletal reorganization from a 6/5/6 tetrahydro‐β‐carboline to a 6/6/5 pyrroloquinoline ring system. Here, we show that this transformation can be achieved by photooxidation with flavin cofactors, such as flavin mononucleotide (FMN) as catalysts.
Shenyu Liu   +6 more
wiley   +2 more sources

A Charge Transfer Mediated Sequential Triplet Energy Transfer Model Beyond the Dexter Limit in Organic Photocatalysis

open access: yesJACS Au
Lin Liu   +9 more
doaj   +1 more source

Light-Driven On-Surface Synthesis: Mechanisms, Strategies, and Architectures. [PDF]

open access: yesNanomaterials (Basel)
Fu Y   +8 more
europepmc   +1 more source

Visible‐Light‐Induced Carbon–Hydrogen Phosphonylation of Conjugated Polymers via Electron Donor–Acceptor Complex Activation

open access: yesAngewandte Chemie, EarlyView.
Electron donor–acceptor (EDA) complex activation enabled the efficient transformation of conjugated polymers. Compared with the small‐molecule model compound, the polymers reacted more efficiently, achieving quantitative conversion of PFO. This result demonstrates a new platform for incorporating conjugated polymers into EDA‐mediated photochemical ...
Tomohiro Tamano   +4 more
wiley   +2 more sources

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