Results 91 to 100 of about 426,040 (306)

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan   +9 more
wiley   +1 more source

Curriculum planning with 'learning outcomes': a theoretical analysis [PDF]

open access: yes, 2007
The use of learning outcomes for curriculum planning is widely advocated in higher education, it is supported by an imposing set of claims, and it has official sanction, for example from the Quality Assurance Agency (QAA). In opposition, there are fierce
Kemp, Brian
core  

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao   +6 more
wiley   +1 more source

Terror, reason, and history

open access: yes, 2011
A striking feature of Barry Hindess' political thought is its unflinching application of theoretical reason to concrete problems. In recent discussion of terrorism, Hindess thus argues against the restricted application of the term to nonstate actors and
Ian Hunter, Hunter, Ian
core   +1 more source

La toute-puissance : entre mythe et raison

open access: yesKentron, 2006
The author suggests studying the relations between reason and affect in the Freudian conception of the myth. Like Lévy-Bruhl who makes confusion between reason and affect by attributing a prelogical thought to the ...
Jacquy Chemouni
doaj   +1 more source

An abstract, argumentation-theoretic approach to default reasoning

open access: yesArtificial Intelligence, 1997
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Andrei Bondarenko   +3 more
openaire   +1 more source

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani   +10 more
wiley   +1 more source

The Glitter and Doom of Theoretical Reason. Interview with Petr Drulák.

open access: yesCzech Journal of International Relations, 2013
V dnešním čísle Mezinárodních vztahů přinášíme čtenářům rozhovor s profesorem Petrem Drulákem. Navazujeme tak na rozhovory s významnými osobnostmi oboru mezinárodních vztahů, které jsme publikovali v letech 2010 a 2011.
Vít Beneš
doaj  

Association Between Motor Pathway Damage and Motor Deficit in Upper and Lower Limb in People With MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corticospinal tract damage is common in people with MS, but the degree of clinical symptoms varies. We hypothesize that corticospinal tract lesions are more extensive and severe in people with MS with motor impairments in both upper and lower limbs.
Mathilde Liffran   +13 more
wiley   +1 more source

MacIntyre, Practical Reason, and Law: Some Remarks

open access: yes, 2022
This contribution aims to highlight some of the aspects of MacIntyre’s approach concerning law and the political-institutional dimension. Taking into account the global theoretical framework elaborated by MacIntyre, law and politics should be regarded as
Giovanni Bombelli
core  

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