Results 71 to 80 of about 369,917 (259)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Razón practica e intelecto agente en Alfarabi

Tópicos, 2013
In this article I seek to show how, for Alfarabi, the agent intellect is not only giver of cognitive forms for the theoretical reason, but rather it also endow to the practical reason with "voluntary intelligibles".
Rafael Ramón Guerrero
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Den argumenterande fornuft

Norsk Filosofisk Tidsskrift, 2017
This paper, on argumentative reason in a modernization-theoretical perspective, is a revised version of a public lecture held at Oslo University College, in memory of Professor Harald Grimen. There are three main points: argumentative reason conceived as
Gunnar Skirbekk
doaj   +1 more source

Theoretical Reasons for Economic Sociology [PDF]

SocioEconomic Challenges, 2017
In this paper I try to justify necessity of developing economic sociology in social sciences. In doing so, I present economic sociology as a sub-discipline. The text draws on the interdisciplinary strengths of economic sociology. The core of the article are arguments why economic sociology may be helpful to understand economic life in better way than ...
openaire   +2 more sources

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Practical wisdom According to Avicennian Philosophy; Its Position, Basis and Its diminution

حکمت سینوی, 2019
Despite the importance of practical wisdom which has not developed in Islamic philosophy, today ,society needs knowledge of ethics and house management and politics.
Mohammadreza Asadi, Gholamreza Badrkhani
doaj  

Reason (Aql) in the Jurisprudential Method of Ibn Idris [PDF]

آموزه‌‌های فقه مدني, 2012
This research has been aimed to show the applied method of Ibn Idris (who influenced the Islamic jurisprudence – Fiqh). The way of the research is to analyze the contents of the influential book of Ibn Idris.
S.M.M. Motalebi, Hasan Jamshidi
doaj  

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source