Results 51 to 60 of about 426,040 (306)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Re-evaluation of the background to the Wellman-Lord process [PDF]

open access: yes, 2001
This project focuses on the determination of the equilibrium partial pressure of sulphur dioxide above aqueous solutions of sodium sulphite / bisulphite typically found in the absorption section of a Wellman-Lord Flue Gas Desulphurisation (FGD) plant ...
Reason, Arthur James
core  

On the rationality of the affective sphere and its relationship with theoretical reason in E. Husserls’s ethics

open access: yesRevista de Filosofia, 2014
The aim of the article is to evaluate to what point does Husserl’s first insight into affective consciousness manage to extend the concept of “reason” to this sphere and analyses whether the way this is accomplished threatens its autonomy regarding ...
Celia Cabrera
doaj   +1 more source

Paradigmatic Ideas in the Critique of Historical Reason in Islam [PDF]

open access: yesتاریخ نگری و تاریخ نگاری, 2018
If we accept that any interpretation of the Islamic heritage of thought is based on a framework of ideas and concepts, which is the title of historical reason, then the continuation of the structure of this historical reason leads to the ineffectiveness ...
Abdolah Motevaly   +2 more
doaj   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Sen’s perfectionist ‘reason to value’

open access: yes, 2015
Amartya Sen, the initiator of the Capability Approach, rejects perfectionism and the idea that theorists can, or ought to, predefine what capabilities we have reason to value.
Jansson, Tulsa
core   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Mill on the Primacy of Practical Reason [PDF]

open access: yes, 2018
In this article, I wish to argue that J.S. Mill holds that theoretical reason is subordinate to practical reason. Ultimately, this amounts to the claim that the norms of theoretical reason – those rules governing how we ought to believe – are grounded in
Macleod, Christopher   +1 more
core   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Deduction of Freedom vs Deduction of Experience in Kant’s Metaphysics

open access: yesКантовский сборник, 2019
My aim is to demonstrate the specificities and differences between transcendental deduction of concepts and deduction of the fundamental principles of pure practical reason in Kant’s metaphysics.
Semyonov V.E
doaj   +1 more source

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