Results 51 to 60 of about 3,091,266 (286)
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Revista de Filosofia, 2014 The aim of the article is to evaluate to what point does Husserl’s first insight into affective consciousness manage to extend the concept of “reason” to this sphere and analyses whether the way this is accomplished threatens its autonomy regarding ...
Celia Cabrera
doaj +1 more source
Theoretical Reasons for Economic Sociology [PDF]
SocioEconomic Challenges, 2017 In this paper I try to justify necessity of developing economic sociology in social sciences. In doing so, I present economic sociology as a sub-discipline. The text draws on the interdisciplinary strengths of economic sociology. The core of the article are arguments why economic sociology may be helpful to understand economic life in better way than ...
openaire +2 more sources
Should Scientific Realists Embrace Theoretical Conservatism? [PDF]
, 2018 A prominent type of scientific realism holds that some important parts of our best current scientific theories are at least approximately true. According to such realists, radically distinct alternatives to these theories or theory-parts are unlikely to ...
Dellsén, Finnur
core +2 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Revista de Estudios Kantianos, 2023 This article attempts to show that the doctrine of the impossibility of total error (DIET) is one of the main presuppositions of Kant's moral thought and not just of his theoretical thought.
Lara Scaglia
doaj +1 more source
Reasons and Theoretical Rationality [PDF]
, 2018 This chapter explores the relationship between reasons and epistemic rationality. In recent debates about rationality and evidence, internalist evidentialism is quite popular. Using this theory as our stalking horse, we examine debates about the ontology of evidence and reasons, a puzzle about rationality and evidential support relations, work on the ...
openaire +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Deduction of Freedom vs Deduction of Experience in Kant’s Metaphysics
Кантовский сборник, 2019 My aim is to demonstrate the specificities and differences between transcendental deduction of concepts and deduction of the fundamental principles of pure practical reason in Kant’s metaphysics.
Semyonov V.E
doaj +1 more source