Results 41 to 50 of about 426,040 (306)

Reasoning about Action: An Argumentation - Theoretic Approach

open access: yesJournal of Artificial Intelligence Research, 2005
We present a uniform non-monotonic solution to the problems of reasoning about action on the basis of an argumentation-theoretic approach. Our theory is provably correct relative to a sensible minimisation policy introduced on top of a temporal propositional logic. Sophisticated problem domains can be formalised in our framework.
Vo, Bao Quoc, Foo, Norman Y.
openaire   +4 more sources

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

CheckMate: Automated Game-Theoretic Security Reasoning

open access: yesProceedings of the 2023 ACM SIGSAC Conference on Computer and Communications Security, 2023
EasyChair Preprint ...
Lea Salome Brugger   +4 more
openaire   +3 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

The problem of antinomy of pure theoretical reason in Kant’s system [PDF]

open access: yesКантовский сборник, 2014
A thorough analysis of the structure of the treatise constituting the first Critique and its comparison with the analogous structure of the second and third Critiques show that the Critique of Pure Reason lacks such an important element as the antinomy ...
Kalinnikov L.
doaj  

Why Study Kant? Framing the Problem

open access: yesКантовский сборник, 2023
In its 2018 publication, Come On! the Club of Rome advocates the need for a New Enlightenment. It associates Kant with an Old Enlightenment that favours (i) individualism, (ii) rationalism and in general (iii) a lack of balance between different elements
Oliver Sensen
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Kant on the Unity of Theoretical and Practical Reason [PDF]

open access: yes, 1998
In his critical works of the 1780's, Kant claims, seemingly inconsistently, that (1) theoretical and practical reason are one and the same reason, applied differently, (2) that he still needs to show that they are, and (3) that theoretical and practical ...
Kleingeld, P., Kleingeld, Pauline
core  

The role and place of reason in justifying religious beliefs from the perspective of Allameh Tabatabai and Thomas Aquinas [PDF]

open access: yesتاریخ فلسفه اسلامی
Allameh considers the intellect to be the soul of human evidence, and the heart is the soul of evidence, thus the receiver of revelation; Self is evidence and it is referred to as heart or intellect.
Mohsen Izadi, Amir Mahdi Shiri
doaj   +1 more source

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