Results 121 to 130 of about 14,381,304 (348)
MAMI Manual v1.0: A Source Manual for the Diagnostic Practical Theory of Structural Exposure
MAMI Manual v1.0 presents the source manual for the diagnostic practical theory of Structural Exposure within MAMI Theory, defined as Meta-Architecture of Mind and Invisibility.
Theory, Mami
core +2 more sources
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Music Theory & Analysis : International journal of the Dutch-Flemish Society for Music Theory.
Samengevoegd met: Music Theory & Analysis Online [ISSN 2295-5925]Voortzetting van: Dutch Journal of Music Theory [ISSN 1385 ...
Dutch-Flemish Society for Music Theory
core
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
This study provides a comprehensive review of the research design, themes, and theoretical development of internship literature in the context of business students.
Edem Maxwell Azila-Gbettor +3 more
doaj +1 more source
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Theories or No Theories—Is Anything Evolving?
Takala, Tuija, Häyry, Matti
openaire +3 more sources
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
The 2010s witnessed intensified debates in international academia on the relationship between theory and forecast, but Russian scholarship remained detached from these discussions. This article intends to examine the contribution of theory to forecasting
I. А. Istomin
doaj +1 more source

