Hypoxia promotes the epithelial‐mesenchymal transition (EMT) of renal tubular epithelial cells via the SIRT1‐FoxO1‐FoxO3‐autophagy pathway, thereby resulting in the fibrosis of renal tubular epithelial cells. Activation of SIRT1 or induction of autophagy inhibits this process, alleviating hypoxia‐induced fibrosis.
Guangyu Wang+6 more
wiley +1 more source
Book Review: Education for Democratic Citizenship. Issues of Theory and Practice, Impact! CPSE for Junior Certificate: Jeanne Barrett and Fiona Richardson, Not Aliens: Primary School Children and the Citlzenship/PSHE Curriculum [PDF]
Yves Laberge, Norma Iredale, Rob Foster
openalex +1 more source
RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer
Analysing RhoA and Rac1 protein levels in Colorectal cancer (CRC) samples under mechanical strain highlights their potential as diagnostic markers. Monitoring their activity could offer valuable insights into how cancer spreads, paving the way for new approaches to better understand and diagnose colorectal cancer.
Sharda Yadav+5 more
wiley +1 more source
Theory and practice in management education: A perspective for Business Schools
Christopher Orpen
openalex +2 more sources
Benchmarking the Quality of Education: Discrepancies and Correspondence between Theory and Practice in 7 European Countries [PDF]
openalex +1 more source
HMGB1 derived from the pyroptotic environment in Hirschsprung‐associated enterocolitis mediates the formation of macrophage extracellular traps through TLR4 ‐p38 MAPK/p65 NF‐kB signaling pathways. Macrophage extracellular traps induce increased ROS production and pyroptosis of colonic epithelial cells.
Rui Zhang+6 more
wiley +1 more source
THE PROBLEMS OF THE THEORY AND PRACTICE OF UNIVERSITY EDUCATION
The paper considers some problems of the theory and practice of University education at the present stage. The ideas of developing the philosophy of higher education were actualized.
N. P. Kirillov, V. N. Fadeeva
doaj
Educational Perspectives on Quaternions: Insights and Applications [PDF]
Quaternions, discovered by Sir William Rowan Hamilton in the 19th century, are a significant extension of complex numbers and a profound tool for understanding three-dimensional rotations. This work explores the quaternion's history, algebraic structure, and educational implications.
arxiv
Book Review: Giving Voice To What We Know: Margaret Newman’s Theory of Health as Expanding Consciousness in Nursing Practice, Research, and Education [PDF]
Pamela G. Reed
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