Frank Gehry’s Self-Twisting Uninterrupted Line: Gesture-Drawings as Indexes
The article analyses Frank Gehry’s insistence on the use of self-twisting uninterrupted line in his sketches. Its main objectives are first, to render explicit how this tendency of Gehry is related to how the architect conceives form-making, and second ...
Marianna Charitonidou
doaj +1 more source
Agent theories, architectures, and languages: A survey [PDF]
The concept of an agent has become important in both Artificial Intelligence (AI) and mainstream computer science. In this article, we present a survey of what we perceive to be the most important theoretical and practical issues associated with the design and construction of intelligent agents.
Michael J. Wooldridge +1 more
openaire +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Theory of Architecture as the Maestro Organising AI Text-to-Image Prompts
In the wake of the Fifth Industrial Revolution, artificial intelligence (AI) has become a disruptive force in architectural design processes. One of its techniques is text-to-image, which generates visual representations from textual descriptions.
Maged Youssef
doaj +1 more source
The Alphabet of Architecture. Originality and Literacy in the Theory of Profiles
In 1691 Augustin-Charles D’Aviler published his Cours d’architecture qui comprend les ordres de Vignole. Ostensibly one of the many extended editions of Vignola’s Regola delli cinque ordini d’architettura (1562) that would appear over the course of the ...
Maarten Delbeke
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Homeownership and Working-Class Suburbs in Barcelona
In comparative analyses, specific features of the Spanish welfare and housing systems have often been emphasized. The case of Barcelona illustrates the extent to which these features are the result of a long-standing historical trajectory and the ...
David Hernández Falagán +3 more
doaj +1 more source
E-Road Network and Urbanization: A Reinterpretation of the Trans-European Petroleumscape
This article examines the role of architecture and urban planning in shaping connections between European land-based mobility, cities and landscapes.
Marianna Charitonidou
doaj +1 more source
Bearing Fault Diagnosis of Split Attention Network Based on Deep Subdomain Adaptation
The insufficient learning ability of traditional convolutional neural network for key fault features, as well as the characteristic distribution of vibration data of rolling bearing collected under variable working conditions is inconsistent, and ...
Haitao Wang, Lindong Pu
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source

