Results 61 to 70 of about 1,295,808 (298)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Mirroring or misting: On the role of product architecture, product complexity, and the rate of product component change [PDF]

open access: yes, 2015
This paper contributes to the literature on the within-firm and across-firm mirroring hypothesis – the assumed architectural mapping between firms’ strategic choices of product architecture and firm architecture, and between firms’ architectural choices ...
Burton, Nicholas
core  

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

open access: yesFEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia   +6 more
wiley   +1 more source

Homeownership and Working-Class Suburbs in Barcelona

open access: yesEncyclopedia
In comparative analyses, specific features of the Spanish welfare and housing systems have often been emphasized. The case of Barcelona illustrates the extent to which these features are the result of a long-standing historical trajectory and the ...
David Hernández Falagán   +3 more
doaj   +1 more source

Topography of Generically Folded Spacecapes: Towards a Cognitive Metatheory in Architectural Design [PDF]

open access: yes, 2017
If we visualize philosophy as a science of the sciences (in the tradition of Hans Heinz Holz), then theories within the philosophical framework are always meta-theories of the respective field of interest in question with which philosophy is actually ...
Koutsandrea, Kanelia   +1 more
core   +1 more source

Prosodic-Enhanced Siamese Convolutional Neural Networks for Cross-Device Text-Independent Speaker Verification

open access: yes, 2018
In this paper a novel cross-device text-independent speaker verification architecture is proposed. Majority of the state-of-the-art deep architectures that are used for speaker verification tasks consider Mel-frequency cepstral coefficients. In contrast,
Dabouei, Ali   +5 more
core   +1 more source

Encoding natural movement as an agent-based system: an investigation into human pedestrian behaviour in the built environment [PDF]

open access: yes, 2002
Gibson's ecological theory of perception has received considerable attention within psychology literature, as well as in computer vision and robotics.
Penn, A, Turner, A
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1429-1452, June 2026.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

What do we mean by building function? [PDF]

open access: yes, 1984
Scientific approaches to architecture usually avoid the issue of building form, preferring to focus on function. But how can there be a theory of function without a systematic analysis of the key architectural variable of form?
Hanson, J., Hillier, B., Peponis, J.
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Home - About - Disclaimer - Privacy