Results 41 to 50 of about 563,485 (262)
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida +6 more
wiley +1 more source
This paper aims to show the evolution of the role and importance of education in economic theory, especially in theoretical approaches to economic development after World War II. In order to find answers and to present a current issue why and how certain countries have made progress while others have regressed in the development process, many theories ...
Osmankovic, Jasmina +2 more
openaire +3 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
La familia: ámbito de humanización del trabajo
La familia como célula básica de la sociedad es el escenario donde se cultivan todas las relaciones sociales posibles. Precisamente por su carácter intrínsecamente asistencial facilita que quienes ejerzan una profesión, bien sea de modo directo, como son
Alfredo Rodríguez Sedano +2 more
doaj
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Tratar sobre el objeto de conocimiento de la educación física requiere, en absoluto, de una mirada atenta a la esencia conceptual, pues siendo a primera vista un compuesto semántico, puede, y ha ocurrido, que se presenten confusiones y, por ende ...
Luis Eduardo Ospina
doaj
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Research on the Error Averaging Effect in A Rolling Guide Pair
By studying the effects of geometric precision on kinematic accuracy, an error mapping model has been established, based on the hypothesis that a motion pair and its installation surface are rigid.
Yanbing Ni +3 more
doaj +1 more source

