Results 41 to 50 of about 991,191 (336)

Does Science Need God? A Theistic Argument from Science

open access: yesReligions, 2021
In our paper, we put forward an argument for the existence of God that starts with a description of the goal of science. The fact that science approximates perfect knowledge opens the problem of its status. We proceed to three resolutions of the problem:
Miłosz Hołda, Jacek Wojtysiak
doaj   +1 more source

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

open access: yesFEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali   +3 more
wiley   +1 more source

The theory of planned behavior and knowledge sharing

open access: yesVINE Journal of Information and Knowledge Management Systems, 2019
Purpose The theory of planned behavior (TPB) is the most frequently used model in knowledge sharing. However, the empirical results are inconclusive on whether TPB can provide reasonable prediction of knowledge sharing behavior (KSB). This study aims to
Tuyet-Mai Nguyen   +2 more
semanticscholar   +1 more source

La síntesis interna de la experiencia sensible. La psicología de Suárez y el origen de la neurociencia

open access: yesScientia et Fides, 2017
En el contexto de la gran síntesis filosófica elaborada por Francisco Suárez entre los siglos XVI y XVII, su comentario al De Anima manifiesta la originalidad de su pensamiento, entre la continuidad y la innovación ante las grandes cuestiones que la obra
José Ángel Lombo
doaj   +1 more source

Religious Pluralism Concept of M. Mendelssohn and Its Theoretical Foundation

open access: yesRUDN Journal of Philosophy, 2020
The article consider the concept of religious pluralism by M. Mendelssohn and some aspects of his theory of knowledge and linguistic theory, lying in the foundation of the pluralism concept. The article shows that Mendelssohn expressed views that are far
L. E Kryshtop
doaj   +1 more source

Taking fishers’ knowledge and its implications to fisheries policy seriously

open access: yesEcology and Society, 2023
Sustainable fishing is one of the most pressing challenges for mankind and requires insightful knowledge of the drivers that may foster or hinder predatory exploitation.
Vitor Renck   +5 more
doaj   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

Čtyři empirické principy Ehrenfrieda Walthera von Tschirnhause

open access: yesFilosofický časopis, 2022
This historically oriented study is dedicated to the German naturalist, mathematician and philosopher Ehrenfried Walther von Tschirnhaus (1651–1708) and aims to introduce his main philosophical-logical work, Medicina mentis. After a biographical overview,
Vrtílka, Pavel
doaj   +1 more source

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

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