Results 51 to 60 of about 5,516,066 (291)
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Teoria cunoștinței: Angajamentele epistemologice tacite ale lui Nicolae Bagdasar
Studii de Istorie a Filosofiei Româneşti, 2021 Through the filter of his specific two steps method in approaching theories of knowledge, Bagdasar seems to invite his interpreter to consider solely the systematic level.
Marius Augustin Drăghici
doaj
Mapping The Understanding Complex in Russell's Theory of Knowledge [PDF]
, 2016 Anyone familiar with Russell’s work on the multiple-relation theory of judgment will at some point have puzzled over the map of the five-term understanding complex at the end of Chapter 1, Part II of his Theory of Knowledge (
Perovic, Katarina
core
Higher-order knowledge and sensitivity [PDF]
, 2020 It has recently been argued that a sensitivity theory of knowledge cannot account for intuitively appealing instances of higher-order knowledge. In this paper, we argue that it can once careful attention is paid to the methods or processes by which we ...
Bjerring, Jens Christian +1 more
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Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
About some aspects of D.I. Mendeleev's world-outlook
Тонкие химические технологии, 2009 In this paper, the section «World outlook» of D.I. Mendeleev's book «Cherished Thoughts» is analyzed. It is shown, what, in Mendeleev's opinion, is the connection between philosophy and science, how important the problem was for him.
A. A. Ivanova
doaj
Scrutinizing the Smart City Index: a multivariate statistical approach [PDF]
Zbornik radova Ekonomskog fakulteta u Rijeci : časopis za ekonomsku teoriju i praksu, 2019 The smart city represents a frequently elaborated concept which however comes short in delivering a consistent definition. Nevertheless, almost every description has always been oriented to its technological component, sustainable ...
Olga Bogdanov +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Le sens de l’être. Heidegger et le néokantisme
Methodos, 2004 It is argued, that Neokantianism – often criticized polemically by Heidegger and his followers –, especially the Neokantianism of his teacher Heinrich Rickert, presents a more thorough theory concerning the fundaments of human understanding than ...
Christian Krijnen
doaj +1 more source