Results 101 to 110 of about 5,901,541 (330)

"The ghost within the ghost in the machine": an interview with Jerome McGann

MatLit, 2016
Focusing mostly on McGann’s recent work, this interview addresses the reasons underlying his critical moves, and looks at his scholarly poetics of interpretation as a material engagement with imaginative works.
Brito, Matheus de, Portela, Manuel
doaj   +1 more source

Gauge Theories of Gravitation

, 2018
During the last five decades, gravity, as one of the fundamental forces of nature, has been formulated as a gauge theory of the Weyl-Cartan-Yang-Mills type.
Blagojević, Milutin, Hehl, Friedrich W.
core  

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

“The Gray House” by Mariam Petrosyan in the context of the literary tradition of magical realism

RUDN Journal of Studies in Literature and Journalism, 2019
The paper deals with a comprehensive analysis of the formal and substantive components of Mariam Petrosyan’s novel “The Gray House” (“The House in Which ...”). The publication of the novel in 2009 provoked extremely diverse criticism.
Vladimir A. Meskin, Lada V. Gaidash
doaj   +1 more source

Spectral fluctuations effects on conductance peak height statistics in quantum dots

, 2002
Within random matrix theory for quantum dots, both the dot's one-particle eigenlevels and the dot-lead couplings are statistically distributed. While the effect of the latter on the conductance is obvious and has been taken into account in the literature,
A. Jalabert, A.G. Huibers, A.G. Huibers, A.M. Chang, B. L. Altshuler, C.W.J. Beenakker, C.W.J. Beenakker, E. Eisenberg, E. Eisenberg, I.L. Aleiner, J.A. Folk, J.A. Folk, K. Held, M.A. Kastner, R.O. Vallejos, S.R. Patel, T. Rupp, Y. Alhassid, Y. Alhassid, Y. Alhassid   +19 more
core   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Set-Theoretic Completeness for Epistemic and Conditional Logic

, 1999
The standard approach to logic in the literature in philosophy and mathematics, which has also been adopted in computer science, is to define a language (the syntax), an appropriate class of models together with an interpretation of formulas in the ...
Halpern, Joseph Y.
core   +4 more sources

Deformed supersymmetric gauge theories from the fluxtrap background

, 2013
The fluxtrap background of string theory provides a transparent and algorithmic way of constructing supersymmetric gauge theories with both mass and Omega-type deformations in various dimensions.
Orlando, Domenico, Reffert, Susanne
core   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source