Results 91 to 100 of about 1,076,493 (308)

A Theory of Thrills, Sublime and Epiphany in Literature

open access: yes, 2022
This book groups together three kinds of experience: the experience of the sublime, of 'epiphany' which is generally a profound experience of something ordinary, and the feeling of 'thrills' which can be a shiver down the spine or sudden tears.
Fabb, Nigel
core  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Traditional Theory of Literature

open access: yes
Through a study of works of the contemporary Indian scholar Ananda K. Coomaraswamy, as well as of other exponents of the ancient doctrine of the Perennial Philosophy, Professor Livingston develops and explicates a traditional theory of literature. Coomar.
Livingston, Ray.
core  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Linguistics and literature [Introduction to theory of Literature]

open access: yes, 2016
Presents a class of Professor Paul H. Fry that talks about the work of Roman Jakobson. He discusses about synchrony and diachrony and about the relationships among formalism, semiotics, and linguistics.
Fry, Paul H.
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Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Russian formalism [Introduction to theory of Literature]

open access: yes, 2016
Presents a class of Professor Paul Fry that talks about the Russian formalism and it's most important authors. He explains Boris Eikhenbaum's essay, which approaches these authors. He also differs the Russian formalism from hermeneuticsEducação Superior::
Fry, Paul H.
core  

A Short History of the Sublime in Polish Literature from a Comparative Perspective [PDF]

open access: yes, 2015
The present book “Poland – History, Culture and Society. Selected Readings” is the third edition of a collection of academic texts written with the intention to accompany the module by providing incoming students with teaching materials that will assist ...
Płuciennik, Jarosław
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Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Russian formalism [Introduction to theory of Literature]

open access: yes, 2011
Educação Superior::Linguística, Letras e Artes::LetrasPresents a class of Professor Paul Fry that talks about the Russian formalism and it's most important authors. He explains Boris Eikhenbaum's essay, which approaches these authors. He also differs the
Fry, Paul H.
core  

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