Results 91 to 100 of about 41,635 (307)

Study of exclusive breastfeeding behaviour based on the theory of planned behaviour in pregnant women in Isfahan in 2021

Family Medicine & Primary Care Review, 2023
GHAZAL KHANJARI, MAJID RAHIMI, NARGES KALANTARI, SHAGHAYEGH AFSHAR, AZARDOKHT CHAHARLANG, FARAHNAZ DEHGHANI, MAHBOOBEH AMINI, MOHAMMAD JAVAD TARRAHI   +7 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Theory of Planned Behaviour and Halal Compliance

International Journal of Academic Research in Business and Social Sciences, 2018
The objective of this paper is to examine the relationship between factors influencing Halal compliance among food truck traders. The factors influencing Halal compliance include behavioural factors (intends, attitude, subjective norm, perceived behavioural control) based on the theory of planned behaviour (TPB) and this paper extends the theory by ...
Noor Raudhiah Abu Bakar, Farah Mohd Shahwahid, Siti Hawa Radin Eksan   +2 more
openaire   +1 more source

Attitudes, norms, identity and environmental behaviour: Using an expanded theory of planned behaviour to predict participation in a kerbside recycling programme [PDF]

, 2010
In an effort to contribute to greater understanding of norms and identity in the theory of planned behaviour, an extended model was used to predict residential kerbside recycling, with self-identity, personal norms, neighbourhood identification, and ...
Lyons, Evanthia, Lyons, E., Uzzell, David, Uzzell, D., Nigbur, Dennis, Nigbur, D.   +5 more
core   +1 more source

Understanding Teachers’ Intention and Behaviour Towards Inclusive Education in Ghana: Applying the Theory of Planned Behaviour

Education Sciences
United Nations Sustainable Development Goal 4 advocates for equitable access to and participation in quality inclusive education for all learners. Inclusive education has gained worldwide recognition for promoting equity and social justice for students ...
Michael Amponteng, Danielle Tracey, William Nketsia   +2 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Predicting Malaysian household food waste behaviour through an integrated framework of theory of planned behaviour (TPB) and theory of interpersonal behaviour (TIB)

Discover Food
Food waste by households is increasing rapidly in developing countries like Malaysia, contributing to environmental damage, higher food costs and threaten reliable food supply.
Ah-Suat Lee, Nurul Afidah Mohamad Yusof, Saw-Chin Khor, Yen-Hong Ng, Suet-Ling Ching, Lin-Sea Lau, Muhammad Rizky Prima Sakti   +6 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source