Results 141 to 150 of about 512,183 (308)
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
THE CONCEPTS OF SPECIALISATION AND SPATIAL CONCENTRATION AND THE PROCESS OF ECONOMIC INTEGRATION: THEORETICAL RELEVANCE AND STATISTICAL MEASURES. THE CASE OF ROMANIA’S REGIONS [PDF]
The issues of specialisation and spatial concentration are important to economic policy and to the competitiveness of the European Union for several reasons.
Ion Lucian Ceapraz
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One of frontiers in agricultural and environmental biotechnology for the arid regions: Micro-pressure drip irrigation technology theory and practices [PDF]
, 2010 With the goal of reducing cost and energy consumption of drip irrigation systems, the relationship between pressure and cost of drip irrigation systems, as well as the feasibility of reducing the operating pressure, were analyzed.
Shao, HB, Wu Pute, Li Jing, Niu Wenquan
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FEBS Open Bio, EarlyView.Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao +3 more
wiley +1 more source
Convergence and divergence in living standards among regions of the enlarged European Union (1992-2006) [PDF]
This paper examines regional convergence in living standards among 264 EU27 regions during1992-2006. The main contribution is the exploratory analysis, which inspects various aspects of regional dynamics such as convergence and divergence, polarization ...
Novotný, JOSEF
core +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
Integration and labour markets in European border regions [PDF]
"Border regions are likely to play a critical role within the spatial dynamics initiated by the enlargement of the EU. This paper deals with the effects of integration on labour markets in border regions.
Niebuhr, Annekatrin, Stiller, Silvia
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Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Spatial econometric analysis of determinants and strategies of FDI in Russian regions in pre- and post-1998 financial crisis periods [PDF]
Using a spatial autoregressive model of cross-sectional and panel data, we study the determinants and dominant strategies of FDI inflows into Russia before and after the 1998 financial crisis.
Ledyaeva, Svetlana
core