Results 121 to 130 of about 512,183 (308)
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Adaptive Localization Regions for O(N) Density Functional Theory [PDF]
, 2008 A linear scaling approach for general and accurate pseudopotential Density Functional Theory calculations is presented. It is based on a Finite Difference discretization.
Fattebert, J
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Anali Hrvatskog Politološkog Društva, 2007 The author analyses the flaws of the multilevel governance theory, which seeks to assert itself as a dominant theory of European integration. The multilevel governance theory begun its life in the work of Gary Marks, who juxtaposed it to functionalist ...
Dario Nikić Čakar
doaj
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
The knowledge regions in the enlarged Europe [PDF]
Since the Lisbon agenda in 2000, Europe stated the goal to become the most advanced knowledge economy in the world relying specifically on the increase and strengthen of its human capital and technological endowments.
Raffaele Paci +2 more
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Determinants of the industrial location in Peru, 1963-1974
EconomíaThe present study responds to the following question: What factors determined the location of manufacturing industries in Peruvian regions for the years 1963 and 1974? Using the data of the Economic Censuses conducted in 1963 and 1974 by the Peruvian
Gonzalo Rivera Mariscal
doaj +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
The economic theory and the Portuguese manufactured industry. Another approach [PDF]
The aim of this paper is to present a further contribution to the analysis of absolute convergence, associated with the neoclassical theory, of the manufactured industry productivity at regional level and for the period from 1995 to 1999 (1)(Martinho ...
Martinho, Vítor João Pereira Domingues
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Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Regions of rationality: Maps for bounded agents [PDF]
An important problem in descriptive and prescriptive research in decision making is to identify “regions of rationality,” i.e., the areas for which heuristics are and are not effective.
Robin Hogarth, Natalia Karelaia
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