Results 91 to 100 of about 281,146 (362)

Design, analysis and reformulation of a didactic sequence for teaching the special theory of relativity in high school

open access: yesRevista Brasileira de Ensino de Física
In this work, we design, implement and analyze a didactic sequence for the teaching of the basic topics of special relativity theory in high school. The sequence proposes a series of situations, specially designed to allow the emergence of the central ...
María Rita Otero   +2 more
doaj   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

The IQ‐compete assay for measuring mitochondrial protein import efficiencies in living yeast cells

open access: yesFEBS Letters, EarlyView.
The efficiency of mitochondrial protein import depends on the properties of the newly synthesized precursor proteins. The Import and de‐Quenching Competition (IQ‐compete) assay is a novel method to monitor the import efficiency of different proteins by fluorescence in living yeast cells.
Yasmin Hoffman   +3 more
wiley   +1 more source

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

open access: yesFEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello   +6 more
wiley   +1 more source

Relativity of simultaneity in secondary school: an analysis based on the Theory of the Conceptual Fields

open access: yesJournal of Physics: Conference Series, 2018
In this paper, we present results about the conceptualization of the relativity of simultaneity and the operational invariants used by high school students. The Theory of Conceptual Fields is adopted to design, analyse and evaluate a didactic sequence to
María Rita Otero   +2 more
semanticscholar   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

La aplicación física de la geometría astral como confirmación de la teoría kantiana del conocimiento

open access: yesLogos, 2007
The appearance of the non-Euclidean or astral geometries seemed to contradict the philosophy of the Kant´s mathematics. He had considered the possibility of a supreme geometry, but he discarded it due to it was not synthetically related with the ...
Juan Cano de Pablo
doaj  

2. The Theory of Special Relativity

open access: yes, 1958
Albert Einstein (1879-1955) published his first work on relativity in 1905, the same year in which he published remarkable papers on Brownian motion and the photoelectric effect.
Bloom, Robert L.   +6 more
core  

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

On the Principle of Relativity of Inertia in Both General and Entangled Relativities [PDF]

open access: yesPhysics of particles and nuclei
Entangled Relativity is a novel theory of relativity that offers a more economical approach than General Relativity. It successfully recovers both General Relativity and standard quantum field theory within a specific (yet generic) limit. Furthermore,
O. Minazzoli
semanticscholar   +1 more source

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