Results 111 to 120 of about 246,583 (327)

L’essenza fenomenologica della relatività. Questioni di confine tra Husserl e Einstein [PDF]

S&F_scienzaefilosofia.it, 2016
The phenomenological Essence of Relativity. Matters concerning the Border between Husserl and Einstein According to Hermann Weyl, Einstein’s Relativity Theory is a method that combines “analysis of essence” and “mathematical construction”.
Giorgio Jules Mastrobisi
doaj  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Shortening: The orthopedic theory of relativity

Journal of Limb Lengthening & Reconstruction, 2020
Dror Paley
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Quantum Gravity as a Broken Symmetry Phase of a BF Theory

Symmetry, Integrability and Geometry: Methods and Applications, 2006
We explain how General Relativity with a cosmological constant arises as a broken symmetry phase of a BF theory. In particular we show how to treat de Sitter and anti-de Sitter cases simultaneously.
Aleksandar Miković
doaj  

Are General Relativity and Teleparallel Gravity Theoretically Equivalent?

Philosophy of Physics
Teleparallel gravity shares many qualitative features with general relativity, but differs from it in the following way: whereas in general relativity, gravitation is a manifestation of spacetime curvature, in teleparallel gravity, spacetime is (always)
James Owen Weatherall, Helen Meskhidze
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Can Lorentz transformations be determined by the null Michelson-Morley result?

Revista Brasileira de Ensino de Física
The so-called principle of relativity is able to fix a general coordinate transformation which differs from the standard Lorentzian form only by an unknown speed which cannot in principle be identified with the light speed.
J. A. S. Lima, Fernando D. Sasse
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Spacetime Emergence: An (In)effective Story

Philosophy of Physics
Physicists and philosophers are increasingly prone to regarding our current physical theories as providing ‘effective descriptions’ of real-world systems.
Mike D. Schneider
doaj   +1 more source