Results 131 to 140 of about 173,551,104 (305)
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Einstein, Gödel, Heidegger. Some observations about the concept of time
Pensamiento. Revista de Investigación e Información Filosófica, 2013 In this article we focus on some of the paths which help us to understand the philosophical question of time. The interpretative frame is composed of Einstein’s theory of relativity, against which we have the observations of Gödel and Heidegger on this ...
Diego Malquori
doaj
Dynamical tidal response of Schwarzschild Black Holes
Journal of High Energy PhysicsDynamical Love numbers capture the conservative response of an object to a time-dependent external tidal gravitational field. We compute the dynamical Love numbers of Schwarzschild black holes in general relativity within a point-particle effective field
Oscar Combaluzier-Szteinsznaider +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
L’essenza fenomenologica della relatività. Questioni di confine tra Husserl e Einstein [PDF]
S&F_scienzaefilosofia.it, 2016 The phenomenological Essence of Relativity. Matters concerning the Border between Husserl and Einstein According to Hermann Weyl, Einstein’s Relativity Theory is a method that combines “analysis of essence” and “mathematical construction”.
Giorgio Jules Mastrobisi
doaj
The Extended Theory of Relativity
This paper combines Albert Einstein's General Theory of Relativity(in which he proposes space-time) and the second law of Thermodynamics(entropy) to propose a new cause for cosmic expansion and to provide justification for a possible beginning and end of the universe.
openaire +2 more sources
On the formal statement of the special principle of relativity [PDF]
, 2011 The aim of the paper is to develop a proper mathematical formalism which can help to clarify the necessary conceptual plugins to the special principle of relativity and leads to a deeper understanding of the principle in its widest ...
Gomori, Marton, Szabo, Laszlo E.
core
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Shortening: The orthopedic theory of relativity
Journal of Limb Lengthening & Reconstruction, 2020 Dror Paley
doaj +1 more source