Results 91 to 100 of about 173,551,104 (305)

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Generalization of Clauses Relative to a Theory [PDF]

open access: yesMachine Learning, 1997
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +1 more source

Relativity as Support for Presentism: A Modest Evidential Argument [PDF]

open access: yes, 2013
Presentism is roughly the view that only the present exists. This view requires an absolute simultaneity relation. The special theory of relativity, however, is highly successful and does not account for absolute simultaneity.
Nasmith, Benjamin B
core  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Electrodynamics in the General Relativity Theory [PDF]

open access: yesProceedings of the National Academy of Sciences, 1924
The restricted relativity theory resulted mathematically in the introduction of pseudo-euclidean four-dimensional space and the welding together of the electric and magnetic force vectors into the electromagnetic tensor. Einstein's general relativity theory led to the assumption that the fourdimensional space mentioned above is a curved space and the ...
openaire   +3 more sources

Relativity theory between structural and dynamical explanations [PDF]

open access: yes, 2006
In this review article I discuss Harvey Brown’s recent book Physical Relativity (OUP, 2005) by presenting and criticizing some of his main arguments in favour of a dynamical underpinning of rods contractions and clocks dilations. The problem about how we
Dorato, Mauro
core  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

The Meaning of Relativity Including the Relativistic Theory of the Non-Symmetric Field (Fifth Edition)

open access: yes, 1945
In 1921, five years after the appearance of his comprehensive paper on general relativity and twelve years before he left Europe permanently to join the Institute for Advanced Study, Albert Einstein visited Princeton University, where he delivered the ...
Greene, Brian, Einstein, Albert
core  

How Hume and Mach Helped Einstein Find Special Relativity [PDF]

open access: yes, 2004
In recounting his discovery of special relativity, Einstein recalled a debt to the philosophical writings of Hume and Mach. I review the path Einstein took to special relativity and urge that, at a critical juncture, he was aided decisively not by any ...
John D. Norton   +2 more
core  

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