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Molecular Imaging and Theragnostics of Thyroid Cancers [PDF]
Cancers, 2022 Molecular imaging plays an important role in the evaluation and management of different thyroid cancer histotypes. The existing risk stratification models can be refined, by incorporation of tumor-specific molecular markers that have theranostic power, to optimize patient-specific (individualized) treatment decisions.
Luca Giovanella +2 more
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Theragnostic nanomotors: Successes and upcoming challenges
WIREs Nanomedicine and Nanobiotechnology, 2021AbstractThe idea of “fantastic voyagers” carrying out medical tasks within the human body has existed as part of popular culture for many decades. The concept revolved around a miniaturized robot that can travel inside the human body and perform complicated functions such as surgery, navigation of otherwise inaccessible biological environments, and ...
Reshma Vasantha Ramachandran +3 more
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Intelligent Micro‐/Nanorobots for Cancer Theragnostic
Advanced Materials, 2022AbstractCancer is one of the most intractable diseases owing to its high mortality rate and lack of effective diagnostic and treatment tools. Advancements in micro‐/nanorobot (MNR)‐assisted sensing, imaging, and therapeutics offer unprecedented opportunities to develop MNR‐based cancer theragnostic platforms.
Jie Wang +7 more
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Ag2S quantum dot theragnostics
Biomaterials Science, 2021Silver sulfide quantum dots (Ag2S QDs) as a theragnostic agent have received much attention because they provide excellent optical and chemical properties to facilitate diagnosis and therapy simultaneously.
Baskaran Purushothaman, Joon Myong Song
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Theragnostics before we found its name
The Quarterly Journal of Nuclear Medicine and Molecular Imaging, 2022Theragnostics embraces "gnosis" and "prognosis" and concerns a treatment strategy which combines diagnostics with therapeutics. The birth of what we call today theragnostics can be traced in 1936, with the proposal of radioiodine, the first radiopharmaceutical approved in 1951 by FDA, in USA, as 131I sodium iodide.
Sergio, Modoni +4 more
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Microbubble pumps: Ultrasound theragnostic agents
The Journal of the Acoustical Society of America, 2015Cardiovascular disease is the number one cause of death worldwide, and thrombo-occlusive disease is a leading cause of morbidity and mortality. Ultrasound has been developed as a tool to induce the release, delivery, and enhanced efficacy of a thrombolytic drug (rt-PA) and bioactive gases from echogenic liposomes.
Christy K. Holland +2 more
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Alpha and Beta Radiation for Theragnostics
PET ClinicsTargeted radionuclide therapy (TRT) has significantly evolved from its beginnings with iodine-131 to employing carrier molecules with beta emitting isotopes like lutetium-177. With the success of Lu-177-DOTATATE for neuroendocrine tumors and Lu-177-PSMA-617 for prostate cancer, several other beta emitting radioisotopes, such as Cu-67 and Tb-161, are ...
Hong, Song, George, Sgouros
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Nanoparticles in Oncology: The New Theragnostic Molecules
Anti-Cancer Agents in Medicinal Chemistry, 2011Cancer nanotherapeutics have shown promise in resolving some of the limitations of conventional drug delivery systems such as nonspecific biodistribution and targeting, lack of water solubility, low therapeutic indices, and poor oral bioavailability. Moreover, cancer nanotechnology has the potential of improving current approaches to cancer detection ...
ALLEGRA, Alessandro +5 more
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Theragnostics applications and challenges
The Quarterly Journal of Nuclear Medicine and Molecular Imaging, 2022Evangelista, Laura, Mansi, Luigi
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Polymeric nanomicelles for cancer theragnostics
International Journal of Polymeric Materials and Polymeric Biomaterials, 2017ABSTRACTRecently, interdisciplinary research in cancer diagnosis and therapy has evolved to the point where nanotechnology particularly polymeric nano delivery systems are utilized for theragnostic applications. Nanoscale are being trialed for specific targeting-delivery of drugs, micelles, antibody, DNA, protein etc.
Anjusha Mohan +2 more
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