Results 81 to 90 of about 2,465 (209)

Construction of an O2‐responsive engineering bioreactor for enhanced indole‐3‐propionic acid production and deoxynivalenol detoxification

open access: yesResponsive Materials, EarlyView.
An oxygen‐responsive living bioreactor was engineered via interspecies protoplast fusion, converting oxygen from an inhibitory stress into a programmable signal for sustained indole‐3‐propionic acid (IPA) production. This genetically encoded bioreactor enables robust aerobic operation and therapeutic efficacy of deoxynivalenol detoxification in vivo ...
Ning Ma   +8 more
wiley   +1 more source

State of the Art Biocompatible Gold Nanoparticles for Cancer Theragnosis

open access: yesPharmaceutics, 2020
Research on cancer theragnosis with gold nanoparticles (AuNPs) has rapidly increased, as AuNPs have many useful characteristics for various biomedical applications, such as biocompatibility, tunable optical properties, enhanced permeability and retention
Moon Sung Kang   +3 more
doaj   +1 more source

Sepsis subphenotypes, theragnostics and personalized sepsis care. [PDF]

open access: yesIntensive Care Med
Heterogeneity between critically ill patients with sepsis is a major barrier to the discovery of effective therapies. The use of machine learning techniques, coupled with improved understanding of sepsis biology, has led to the identification of patient subphenotypes.
Antcliffe DB   +5 more
europepmc   +4 more sources

Monoaminergic Neuropathology in Alzheimer's disease [PDF]

open access: yes, 2016
Acknowledgments This work was supported by The Croatian Science Foundation grant. no. IP-2014-09-9730 (“Tau protein hyperphosphorylation, aggregation, and trans-synaptic transfer in Alzheimer’s disease: cerebrospinal fluid analysis and assessment of ...
Bažadona, Danira   +11 more
core   +1 more source

The scale matters: A review on stimuli‐responsive microrobots categorized by scale for biomedical applications

open access: yesResponsive Materials, EarlyView.
We systematically summarize how each scale dictates fundamental choices in design feature, manufacturing technology, driving mechanism, and control strategy, which are inherently governed by scale‐dominated physical principles. Furthermore, the application of scale‐determined operation modes of microrobots across different stages of medical ...
Hang Yin   +3 more
wiley   +1 more source

Imparting Biodegradability to Highly‐Efficient Upconversion Nanoparticles via Facet‐Selective Zirconium Doping

open access: yesSmall, EarlyView.
A simple incorporation of Zr imparts biodegradability to inherently inert rare‐earth‐based upconversion nanoparticles without compromising optical performance. Surface energy modulation of LiREF4 facets by a binary‐surfactant system enables Zr incorporation during hot‐injection synthesis.
Murad M. A. Abualrejal   +6 more
wiley   +1 more source

Theragnostics - alternative production of terbium isotopes at the University of Birmingham using an MC40 cyclotron [PDF]

open access: yes, 2020
In this work alternative methods for the production of terbium isotopes, and in particular 152Tb and 155Tb, have been investigated. These isotopes, which could be used for theragnostics, have been produced using an alpha and a proton beam incident on ...
Allen, Ross   +15 more
core   +1 more source

Nuclear Medicine and Cancer Theragnostics

open access: yes, 2023
Cancer theragnostics is a novel approach that combines diagnostic imaging and radionuclide therapy. It is based on the use of a pair of radiopharmaceuticals, one optimized for positron emission tomography imaging, through linkage to a proper radionuclide, and the other bearing a beta-emitter isotope that can induce significant damage to cancer cells ...
Vasiliki Zoi   +8 more
openaire   +1 more source

A Retrospective Comparative Study of Sodium Fluoride (NaF-18)-PET/CT and Fluorocholine (F-18-CH) PET/CT in the Evaluation of Skeletal Metastases in Metastatic Prostate Cancer Using a Volumetric 3-D Radiomics Analysis

open access: yesDiagnostics, 2020
Bone metastases are common in prostate cancer (PCa). Fluorocholine-18 (FCH) and sodium fluoride-18 (NaF) have been used to assess PCa associated skeletal disease in thousands of patients by demonstrating different mechanism of uptake-cell membrane (lipid)
Kalevi Kairemo   +3 more
doaj   +1 more source

Activatable smart contrast agents for photoacoustic imaging

open access: yesSmart Molecules, EarlyView.
This review highlights recent advances in smart activatable photoacoustic imaging (PAI) contrast agents, which dynamically modulate their optical properties in response to external stimuli or microenvironmental cues. It discusses their molecular design, activation mechanisms, biomedical applications, and future prospects for clinically tailored use ...
Donghyeon Oh   +5 more
wiley   +1 more source

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