Results 81 to 90 of about 1,533 (199)

Targeted radionuclide therapy and diagnostic imaging of SSTR positive neuroendocrine tumors: a clinical update in the new decade

Frontiers in Nuclear Medicine
Neuroendocrine tumors (NETs) are a heterogeneous group of neoplasms characterized by their overexpression of somatostatin receptors (SSTRs), which can be utilized for peptide receptor radionuclide therapy.
Katherine N. Haugh, Alexis M. Sanwick, Ivis F. Chaple   +2 more
doaj   +1 more source

PET/CT and PET/MRI in Cancer Diagnosis and Management: A Comparative Clinical Perspective

iMetaMed, Volume 2, Issue 2, June 2026.
This review compares PET/CT and PET/MRI in cancer imaging, highlighting their complementary roles for precise diagnosis and staging. It evaluates their technical strengths, clinical performance across various cancers, and future directions, including AI and novel tracers.
Zijian Ding, Ran Xue, Qianxi Jin, Wangzheqi Zhang, Yali Wu, Baixuan Xu   +5 more
wiley   +1 more source

Mapping translational research in personalized therapeutics: from molecular markers to health policy [PDF]

, 2007
Translational research is frequently used in the bioscience literature to refer to the translation of basic science into practical applications at the point of patient care.
Someya, Toshiyuki, Godard, Béatrice, Williams-Jones, Bryn, Cooper, Dan M, Ozdemir, Vural, Godard, Batrice, Cooper, Dan M.   +6 more
core   +1 more source

Extracellular Vesicles as Enabling Biomarkers for New Approach Methodologies to Support the US Food and Drug Administration Modernization Act 3.0

Journal of Extracellular Vesicles, Volume 15, Issue 6, June 2026.
ABSTRACT The FDA Modernization Act 3.0 represents a pivotal shift in biomedical research by formally removing the requirement for animal testing and enabling regulatory acceptance of New Approach Methodologies (NAMs). This transition creates an urgent need for robust, human‐relevant biomarkers that can anchor NAM‐generated data within regulatory ...
Andrew Rowland, Carl Kirkpatrick, A David Rodrigues, Uli Frevert, Franziska Haderk, David W Greening, Andrew J McLachlan, Ashley Hopkins, Fabrice Lucien, Rienk Nieuwland   +9 more
wiley   +1 more source

From Monte Carlo PET Simulations to Reconstructed Images [Elektronisk resurs] : Modelling and Optimisation for 68Ga Theragnostics

, 2023
In nuclear medicine, radiopharmaceuticals can be administered for both diagnostic and therapeutic purposes. In recent years, there has been an increasing interest in theragnostics, a strategy that combines both diagnosis and therapy. This can be achieved
Kalaitzidis, Philip,, Lund University.
core  

Shaping Function: Polymeric 3D Systems With Unconventional Geometries for Biomedical Applications

Small, Volume 22, Issue 33, 12 June 2026.
Particle shape is a key design parameter governing biological interactions. Advances in fabrication enable precise control over anisotropy and compartmentalization, allowing modulation of cellular uptake, transport, and biodistribution, ultimately enhancing therapeutic performance. ABSTRACT Polymer geometry is a primary determinant of physical behavior
Francisca G. Perfeito, Mariana B. Oliveira, João F. Mano   +2 more
wiley   +1 more source

Sepsis subphenotypes, theragnostics and personalized sepsis care. [PDF]

Intensive Care Med
Heterogeneity between critically ill patients with sepsis is a major barrier to the discovery of effective therapies. The use of machine learning techniques, coupled with improved understanding of sepsis biology, has led to the identification of patient ...
Antcliffe DB, Burrell A, Boyle AJ, Gordon AC, McAuley DF, Silversides J.   +5 more
europepmc   +2 more sources

Imparting Biodegradability to Highly‐Efficient Upconversion Nanoparticles via Facet‐Selective Zirconium Doping

Small, Volume 22, Issue 32, 8 June 2026.
A simple incorporation of Zr imparts biodegradability to inherently inert rare‐earth‐based upconversion nanoparticles without compromising optical performance. Surface energy modulation of LiREF4 facets by a binary‐surfactant system enables Zr incorporation during hot‐injection synthesis.
Murad M. A. Abualrejal, Byeong‐Seok Moon, Tae Kyung Lee, Sein Kim, Hyunbin Yu, Sungsu Park, Dong‐Hwan Kim   +6 more
wiley   +1 more source

Terbium sisters: current development status and upscaling opportunities

Frontiers in Nuclear Medicine
The interest in terbium radionuclides, which can be used in nuclear medicine, has increased tremendously over the last decade. Several research studies have shown the potential of four terbium radionuclides 149,152,155,161Tb both for cancer diagnosis as ...
Anzhelika N. Moiseeva, Chiara Favaretto, Chiara Favaretto, Zeynep Talip, Pascal V. Grundler, Nicholas P. van der Meulen, Nicholas P. van der Meulen   +6 more
doaj   +1 more source

Predictive Immunohistochemistry in Cholangiocarcinoma: Current Clinical Utility, Practical Limitations, and Emerging Directions

APMIS, Volume 134, Issue 6, June 2026.
ABSTRACT Cholangiocarcinoma (CCA) remains a difficult‐to‐treat biliary malignancy in which therapeutic stratification increasingly depends on predictive biomarkers. Although next‐generation sequencing is essential for the detection of targetable genomic alterations, immunohistochemistry (IHC) retains a practical role because it is widely available ...
Francesco Vasuri, Alessandra Boccaccino, Stefano Tamberi, Luca Saragoni   +3 more
wiley   +1 more source