Results 1 to 10 of about 47,372 (142)
Multifunctional theranostic nanomedicines for cancer treatment: Recent progress and challenges
This review intends to provide the essentially manufacturing of various types of nanomedicines utilized for the treatment of different cancers. Nanomedicine is an advanced field of research in medicine combined with nanomaterials, which is the very ...
Laxmanan Karthikeyan +4 more
doaj +1 more source
With the emergence of disease modifying osteoarthritis drugs (DMOAD), imaging methods to quantitatively demonstrate their efficacy and to monitor osteoarthritis progression at the functional level are urgently needed.
Arnaud Briat +9 more
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Intracoronary optical coherence tomography (OCT) requires injection of flushing media for image acquisition. Alternative flushing media needs to be investigated to reduce the risk of contrast-induced renal dysfunction. We investigated the feasibility and
Dong Oh Kang +4 more
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High-fidelity carbon dots polarity probes: revealing the heterogeneity of lipids in oncology
Polarity is an integral microenvironment parameter in biological systems closely associated with a multitude of cellular processes. Abnormal polarity variations accompany the initiation and development of pathophysiological processes.
Jingyu Hu +7 more
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Targeted theranostic photoactivation on atherosclerosis
Background Photoactivation targeting macrophages has emerged as a therapeutic strategy for atherosclerosis, but limited targetable ability of photosensitizers to the lesions hinders its applications.
Joon Woo Song +13 more
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Blood-brain barrier transport kinetics of NOTA-modified proteins : the somatropin case [PDF]
BACKGROUND: Chemical modifications such as PEG, polyamine and radiolabeling on proteins can alter their pharmacokinetic behaviour and their blood-brain barrier (BBB) transport characteristics. NOTA, i.e. 1,4,7-triazacyclononane-1,4,7-triacetic acid, is a
Bracke, Nathalie +7 more
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Expression of the First Recombinant Anti-Tumoral Snake Venom Kunitz-Type Serine Protease Inhibitor
PIVL is a Kunitz-type serine protease inhibitor that was previously characterized from Tunisian snake venom, Macrovipera lebetina transmediterranea. It reduced glioblastoma cells’ development and significantly blocked angiogenesis in in-vitro and ex-vivo
Maram Morjen +6 more
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Natural coumarin derivatives and cyclometallic iridium (Ⅲ) (IrⅢ) complexes have attracted much attention in the field of anticancer. In this study, six coumarin-modified cyclometallic IrⅢ salicylaldehyde Schiff base complexes ([(ppy)2Ir(O^N)]/[(ppy-CHO ...
Ruixi Xu +4 more
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Melanocortin 1 receptor targeted imaging of melanoma with gold nanocages and positron emission tomography [PDF]
Purpose: Melanoma is a lethal skin cancer with unmet clinical needs for targeted imaging and therapy. Nanoscale materials conjugated with targeting components have shown great potential to improve tumor delivery efficiency while minimizing undesirable ...
Black, Kvar +8 more
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Image-guided therapy using maghemite-MOF nanovectors [PDF]
Advances in nanotechnology offer the possibility of tailored delivery of therapeutics with real-time imaging of disease. In this issue of Chem, Steunou and co-workers amalgamate the powerful MRI properties of ultra-small paramagnetic iron oxides with the
Abánades Lázaro, Isabel +1 more
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