Results 1 to 10 of about 47,372 (142)

Multifunctional theranostic nanomedicines for cancer treatment: Recent progress and challenges

open access: yesBiomedical Engineering Advances, 2023
This review intends to provide the essentially manufacturing of various types of nanomedicines utilized for the treatment of different cancers. Nanomedicine is an advanced field of research in medicine combined with nanomaterials, which is the very ...
Laxmanan Karthikeyan   +4 more
doaj   +1 more source

99mTc-NTP 15-5 is a companion radiotracer for assessing joint functional response to sprifermin (rhFGF-18) in a murine osteoarthritis model

open access: yesScientific Reports, 2022
With the emergence of disease modifying osteoarthritis drugs (DMOAD), imaging methods to quantitatively demonstrate their efficacy and to monitor osteoarthritis progression at the functional level are urgently needed.
Arnaud Briat   +9 more
doaj   +1 more source

Feasibility and safety of non-contrast optical coherence tomography imaging using hydroxyethyl starch in coronary arteries

open access: yesScientific Reports, 2023
Intracoronary optical coherence tomography (OCT) requires injection of flushing media for image acquisition. Alternative flushing media needs to be investigated to reduce the risk of contrast-induced renal dysfunction. We investigated the feasibility and
Dong Oh Kang   +4 more
doaj   +1 more source

High-fidelity carbon dots polarity probes: revealing the heterogeneity of lipids in oncology

open access: yesLight: Science & Applications, 2022
Polarity is an integral microenvironment parameter in biological systems closely associated with a multitude of cellular processes. Abnormal polarity variations accompany the initiation and development of pathophysiological processes.
Jingyu Hu   +7 more
doaj   +1 more source

Targeted theranostic photoactivation on atherosclerosis

open access: yesJournal of Nanobiotechnology, 2021
Background Photoactivation targeting macrophages has emerged as a therapeutic strategy for atherosclerosis, but limited targetable ability of photosensitizers to the lesions hinders its applications.
Joon Woo Song   +13 more
doaj   +1 more source

Blood-brain barrier transport kinetics of NOTA-modified proteins : the somatropin case [PDF]

open access: yes, 2020
BACKGROUND: Chemical modifications such as PEG, polyamine and radiolabeling on proteins can alter their pharmacokinetic behaviour and their blood-brain barrier (BBB) transport characteristics. NOTA, i.e. 1,4,7-triazacyclononane-1,4,7-triacetic acid, is a
Bracke, Nathalie   +7 more
core   +1 more source

Expression of the First Recombinant Anti-Tumoral Snake Venom Kunitz-Type Serine Protease Inhibitor

open access: yesToxins, 2022
PIVL is a Kunitz-type serine protease inhibitor that was previously characterized from Tunisian snake venom, Macrovipera lebetina transmediterranea. It reduced glioblastoma cells’ development and significantly blocked angiogenesis in in-vitro and ex-vivo
Maram Morjen   +6 more
doaj   +1 more source

Lysosomal Targeted Cyclometallic Iridium(Ⅲ) Salicylaldehyde-Coumarin Schiff Base Complexes and Anticancer Application

open access: yesFrontiers in Chemistry, 2022
Natural coumarin derivatives and cyclometallic iridium (Ⅲ) (IrⅢ) complexes have attracted much attention in the field of anticancer. In this study, six coumarin-modified cyclometallic IrⅢ salicylaldehyde Schiff base complexes ([(ppy)2Ir(O^N)]/[(ppy-CHO ...
Ruixi Xu   +4 more
doaj   +1 more source

Melanocortin 1 receptor targeted imaging of melanoma with gold nanocages and positron emission tomography [PDF]

open access: yes, 2018
Purpose: Melanoma is a lethal skin cancer with unmet clinical needs for targeted imaging and therapy. Nanoscale materials conjugated with targeting components have shown great potential to improve tumor delivery efficiency while minimizing undesirable ...
Black, Kvar   +8 more
core   +2 more sources

Image-guided therapy using maghemite-MOF nanovectors [PDF]

open access: yes, 2017
Advances in nanotechnology offer the possibility of tailored delivery of therapeutics with real-time imaging of disease. In this issue of Chem, Steunou and co-workers amalgamate the powerful MRI properties of ultra-small paramagnetic iron oxides with the
Abánades Lázaro, Isabel   +1 more
core   +1 more source

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