Results 11 to 20 of about 22,478 (243)
Mitochondria-targeting theranostics [PDF]
Biomaterials Research, 2018 Background Interest in subcellular organelle-targeting theranostics is substantially increasing due to the significance of subcellular organelle-targeting drug delivery for maximizing therapeutic effects and minimizing side effects, as well as the ...
Han Chang Kang
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Molecular theranostics: principles, challenges and controversies
Journal of Medical Radiation SciencesTheranostics is a new term for long‐established principles in nuclear medicine. The generalisability of the term means there is a very broad use of the term across the medical literature, not all of which is consistent with the intent in nuclear medicine.
Geoffrey Currie
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Theranostic Nanoparticles [PDF]
Journal of Nuclear Medicine, 2014 Theranostic nanoparticles hold the potential to revolutionize disease management. Over the last decade, there has been growing interest in the engineering of various kinds of theranostic nanoparticles for simultaneous cancer imaging and therapy in small animals.
Feng, Chen +2 more
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The Current Status and Future Potential of Theranostics to Diagnose and Treat Childhood Cancer
Frontiers in Oncology, 2020 In theranostics (i.e., therapy and diagnostics) radiopharmaceuticals are used for both therapeutic and diagnostic purposes by targeting one specific tumor receptor.
Alex J. Poot +3 more
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Theranostics in Hematooncology
Journal of Nuclear Medicine, 2023 In the early 2000s, major clinical trials provided evidence of a favorable outcome from antibody-mediated radioimmunotherapy for hematologic neoplasms, which then led to Food and Drug Administration approval. For instance, the theranostic armamentarium for the referring hematooncologist now includes 90Y-ibritumomab tiuxetan for refractory low-grade ...
Buck, Andreas K. +8 more
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Models of Models: A Translational Route for Cancer Treatment and Drug Development
Frontiers in Oncology, 2017 Every patient and every disease is different. Each patient therefore requires a personalized treatment approach. For technical reasons, a personalized approach is feasible for treatment strategies such as surgery, but not for drug-based therapy or drug ...
Lesley A. Ogilvie +5 more
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Aggregation‐enhanced theranostics: AIE sparkles in biomedical field
Aggregate, 2020 Theranostics referring to the ingenious integration of diagnostics and therapeutics has garnered tremendous attention in these years as it provides a promising opportunity for modern personalized and precision medicine.
Miaomiao Kang +7 more
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Neuroendocrine tumor theranostics
Cancer Science, 2022 AbstractTheranostics is a term coined by combining the words “therapeutics” and “diagnostics,” referring to single chemical entities developed to deliver therapy and diagnosis simultaneously. Neuroendocrine tumors are rare cancers that occur in various organs of the body, and they express neuroendocrine factors such as chromogranin A and somatostatin ...
Yasushi Ichikawa +5 more
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Targeting neuropilin-1 interactions is a promising anti-tumor strategy
Chinese Medical Journal, 2021 . Neuropilins (NRP1 and NRP2) are multifunctional receptor proteins that are involved in nerve, blood vessel, and tumor development. NRP1 was first found to be expressed in neurons, but subsequent studies have demonstrated its surface expression in cells
Shao-Dan Liu +4 more
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Theranostics, 2017 DNAzymes are catalytically active DNA molecules that are obtained via in vitro selection. RNA-cleaving DNAzymes have attracted significant attention for both therapeutic and diagnostic applications due to their excellent programmability, stability, and activity. They can be designed to cleave a specific mRNA to down-regulate gene expression.
Zhou, Wenhu, Ding, Jinsong, Liu, Juewen
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