Results 41 to 50 of about 69,322 (198)

Chronic Inflammation Links Cancer and Parkinson’s disease

Frontiers in Aging Neuroscience, 2016
An increasing number of genetic studies suggest that the pathogenesis of Parkinson’s disease (PD) and cancer share common genes, pathways, and mechanisms.
Zhiming eLi, Zhiming eLi, Zaozao eZheng, Zaozao eZheng, Jun eRuan, Jun eRuan, Zhi eLi, Zhi eLi, Chi-Meng eTzeng, Chi-Meng eTzeng, Chi-Meng eTzeng   +10 more
doaj   +1 more source

40P Development of radiolabelled plerixafor as a theranostic molecule for targeting CXCR4 receptor expressing cancers: A translational study [PDF]

, 2023
T. Lakhanpal, B.R. Mittal, J. Shukla, R. Kumar, Y. Rathore, Pankaj Malhotra, G. Prakash, A. Khadwal, A. Bal   +8 more
openalex   +1 more source

Molecular theranostics: principles, challenges and controversies

Journal of Medical Radiation Sciences
Theranostics is a new term for long‐established principles in nuclear medicine. The generalisability of the term means there is a very broad use of the term across the medical literature, not all of which is consistent with the intent in nuclear medicine.
Geoffrey Currie
doaj   +1 more source

Patient-Specific Dosimetry Evaluations in Theranostics Software for Internal Radiotherapy

Applied Sciences
In Internal Radiotherapy, radiopharmaceutical dosimetry provides an accurate estimation of absorbed radiation doses to organs at risk and tumours. In this paper Velocity Theranostics (Varian Medical Systems), is investigated.
Elisa Grassi, Domenico Finocchiaro, Federica Fioroni, George Andl, Angelina Filice, Annibale Versari, Ayman El Ouati, Emiliano Spezi, Mauro Iori   +8 more
doaj   +1 more source

PET/PDT theranostics: Synthesis and biological evaluation of a peptide-targeted gallium porphyrin [PDF]

, 2015
The development of novel theranostic agents is an important step in the pathway towards personalised medicine, with the combination of diagnostic and therapeutic modalities into a single treatment agent naturally lending itself to the optimisation and ...
Boyle, Ross W., Bryden, Francesca, Rosca, Elena V., Savoie, Huguette   +3 more
core   +1 more source

Frequency Doubling Nanocrystals for Cancer Theranostics

, 2013
A novel bio-photonics approach based on the nonlinear optical process of second harmonic generation by non-centrosymmetric nanoparticles is presented and demonstrated on malignant human cell lines. The proposed method allows to directly interact with DNA
Bonacina, Luigi, Dubled, Marc, Gerber-Lemaire, Sandrine, Magouroux, Thibaud, Passemard, Solène, Rytz, Daniel, Schneiter, Guillaume Stéphane, Schwung, Sebastian, Staedler, Davide, Wolf, Jean-Pierre   +9 more
core   +4 more sources

A plug-and-play approach to antibody-based therapeutics via a chemoselective dual click strategy. [PDF]

, 2015
Although recent methods for the engineering of antibody-drug conjugates (ADCs) have gone some way to addressing the challenging issues of ADC construction, significant hurdles still remain.
Caddick, S, Chester, KA, Chudasama, V, Maruani, A, Miranda, E, Smith, ME   +5 more
core   +1 more source

MiR675-5p acts on HIF-1α to sustain hypoxic responses: A new therapeutic strategy for glioma [PDF]

, 2016
Hypoxia is a common feature in solid tumours. In glioma, it is considered the major driving force for tumour angiogenesis and correlates with enhanced resistance to conventional therapies, increased invasiveness and a poor prognosis for patients. Here we
Alessandro, Riccardo, Conigliaro, Alice, Costa, Viviana, Diceglie, Cecilia, Dico, Alessia Lo, Mancone, Carmine, Martelli, Cristina, Ottobrini, Luisa, Rajata, Francesca, Rizzo, Aroldo, Tripodi, Marco   +10 more
core   +3 more sources

Pepducin-mediated cardioprotection via β-arrestin-biased β2-adrenergic receptor-specific signaling [PDF]

, 2018
Reperfusion as a therapeutic intervention for acute myocardial infarction-induced cardiac injury itself induces further cardiomyocyte death. β-arrestin (βarr)-biased β-adrenergic receptor (βAR) activation promotes survival signaling responses in vitro ...
Benovic, Jeffrey L., Carter, Rhonda L., de Lucia, Claudio, Gao, Erhe, Grisanti, Laurel A., Koch, Walter J., Thomas, Toby P., Tilley, Douglas G.   +7 more
core   +1 more source

Preclinical Applications of 3'-Deoxy-3'-[18F]Fluorothymidine in Oncology - A Systematic Review [PDF]

, 2016
The positron emission tomography (PET) tracer 3'-deoxy-3'-[18F]fluorothymidine ([18F]FLT) has been proposed to measure cell proliferation non-invasively in vivo. Hence, it should provide valuable information for response assessment to tumor therapies. To
Aboagye, E, Bollineni, V, Heinzmann, K, Jacobs, A, Kramer, G, Liu, Y, Schelhaas, S, Shields, A, Soloviev, D, Waterton, J   +9 more
core   +1 more source