Results 1 to 10 of about 3,095,595 (149)
Frontiers in Pharmacology, 2023 Aberrant activity of the cysteine protease Cathepsin S (CTSS) has been implicated across a wide range of pathologies. Notably in cancer, CTSS has been shown to promote tumour progression, primarily through facilitating invasion and migration of tumour ...
P. Smyth +12 more
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Emerging Insights on Caspases in COVID-19 Pathogenesis, Sequelae, and Directed Therapies
Frontiers in Immunology, 2022 Coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), remains a significant global health emergency with new variants in some cases evading current therapies and approved vaccines.
Thomas A. Premeaux +7 more
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Pharmaceutics, 2021 Proteases are involved in the control of numerous physiological processes, and their dysregulation has been identified in a wide range of pathologies, including cancer.
Bruce Howng +5 more
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Potential Role of Natural Products to Combat Radiotherapy and Their Future Perspectives
Molecules, 2021 Cancer is the second leading cause of death in the world. Chemotherapy and radiotherapy (RT) are the common cancer treatments. In addition to these limitations, the development of adverse effects from chemotherapy and RT reduces the quality of life for ...
Rokeya Akter +8 more
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Pyridine Scaffolds, Phenols and Derivatives of Azo Moiety: Current Therapeutic Perspectives
Molecules, 2021 Synthetic heterocyclic compounds have incredible potential against different diseases; pyridines, phenolic compounds and the derivatives of azo moiety have shown excellent antimicrobial, antiviral, antidiabetic, anti-melanogenic, anti-ulcer, anticancer ...
Tehreem Tahir +6 more
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Marine Drugs, 2022 Microalgae have been identified as one of the most promising sources of novel bioactive compounds for biomedical applications, the food industry, and cosmetics. In the last decade, several biotechnological developments have facilitated the identification
Jezabel Garcia-Parra +2 more
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Evaluation of Prophylactic and Therapeutic Effects of Silymarin on Phenobar- bital-Induced Hepatotoxicity in Cats [PDF]
Iranian Journal of Veterinary Medicine, 2020 BACKGROUND: Phenobarbital is one of the most commonly used drugs to treat epilepsy and other seizure disorders in dogs and cats. Hepatotoxicity following phenobarbital administration is dose-dependent.
Bahman Mosallanejad +3 more
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Coenzyme Q10 and Its Therapeutic Potencies Against COVID-19 and Other Similar Infections: A Molecular Review [PDF]
Advanced Pharmaceutical Bulletin, 2023 Purpose: New lethal coronavirus disease 2019 (COVID-19), currently, has been converted to a disastrous pandemic worldwide. As there has been found no definitive treatment for the infection in this review we focused on molecular aspects of coenzyme Q10 ...
Mohammad Fakhrolmobasheri +6 more
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Laminin and Integrin in LAMA2-Related Congenital Muscular Dystrophy: From Disease to Therapeutics
Frontiers in Molecular Neuroscience, 2020 Laminin-α2-related congenital muscular dystrophy (LAMA2-CMD) is a devastating neuromuscular disease caused by mutations in the LAMA2 gene. These mutations result in the complete absence or truncated expression of the laminin-α2 chain.
Pamela Barraza-Flores +3 more
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Anniversary of Academician of the Russian Academy of Sciences, Professor Alexander G. Chuchalin [PDF]
Терапевтический архив, 2020 Alexander Grigorievich Chuchalin is a world-famous scientist, an outstanding representative of modern Russian medical science and practical health care, the founder of a whole area in Russian medicine - pulmonology.
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