Treatment Eligibility and Therapeutic Responses of an Ecuadorian Population at High Cardiovascular Risk Based on the ATP III Guidelines [PDF]
, 2020 Isabel Hernández +8 more
openalex +1 more source
Personal Investigator: A Therapeutic 3D Game for Adolescent Psychotherapy [PDF]
, 2005 Coyle, David +4 more
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
theRNA: a curated knowledgebase of functional RNA therapeutics spanning diverse modalities and disease applications. [PDF]
Nucleic Acids ResZhou Y +10 more
europepmc +1 more source
FEBS Letters, EarlyView.At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source
The Role of Academic Medical Centers in Personalized Experimental Therapeutic Development: Key Considerations. [PDF]
NeurologyDies KA +9 more
europepmc +1 more source
Hamate’s coronal fracture: diagnostic and therapeutic approaches based on a long-term follow-up
, 2019 Christian Eder +3 more
openalex +1 more source
Combination of topical agents and oxybutynin as a therapeutic modality for patients with both osmidrosis and hyperhidrosis [PDF]
, 2018 Andrea Yasbek Monteiro Varella +7 more
openalex +1 more source