Results 41 to 50 of about 5,700,393 (345)

Predictive Variables for Interventional Angiography among Patients with Knee Hemarthrosis

Diagnostics, 2022
Studies regarding the variables that could predict the success of conservative treatment for knee hemarthrosis are lacking. This retrospective study evaluated the laboratory variables of patients who had unsatisfactory results from conservative treatment
Sang-Hun Ko, Kwang-Hwan Jung, Jae-Ryong Cha, Ki-Bong Park   +3 more
doaj   +1 more source

Design of therapeutic biomaterials to control inflammation

Nature Reviews Materials, 2022
Inflammation plays an important role in the response to danger signals arising from damage to our body and in restoring homeostasis. Dysregulated inflammatory responses occur in many diseases, including cancer, sepsis and autoimmunity.
Zhaoxu Tu, Yiling Zhong, Hanze Hu, Dan Shao, R. Haag, M. Schirner, Jaewoo Lee, B. Sullenger, Kam W. Leong   +8 more
semanticscholar   +1 more source

In memory of academician V.I. Pokrovsky (04/01/1929 - 10/29/2020)

Терапевтический архив, 2020
In memory of academician V.I. Pokrovsky (04/01/1929 - 10/29/2020)
Collegium of the journal "Therapeutic archive"
doaj  

Lipogenesis inhibitors: therapeutic opportunities and challenges

Nature reviews. Drug discovery, 2022
Fatty acids are essential for survival, acting as bioenergetic substrates, structural components and signalling molecules. Given their vital role, cells have evolved mechanisms to generate fatty acids from alternative carbon sources, through a process ...
Battsetseg Batchuluun, Stephen L. Pinkosky, G. Steinberg   +2 more
semanticscholar   +1 more source

Plant derived bioactive compounds for the treatment of neurodegeneration and neuroimmune disorders associated with the complement system

Exploration of Immunology
The complement system is a key component of the innate immune system that mediates the clearance of pathogens, apoptotic cells, and cellular debris.
Jeyaparthasarathy Narayanaperumal, Ganesh Gopal   +1 more
doaj   +1 more source

Patisiran, an RNAi Therapeutic, for Hereditary Transthyretin Amyloidosis

New England Journal of Medicine, 2018
BACKGROUND Patisiran, an investigational RNA interference therapeutic agent, specifically inhibits hepatic synthesis of transthyretin. METHODS In this phase 3 trial, we randomly assigned patients with hereditary transthyretin amyloidosis with ...
D. Adams, A. González-Duarte, W. O'Riordan, Chih-Chao Yang, M. Ueda, A. Kristen, I. Tournev, H. Schmidt, T. Coelho, J. Berk, Kon-Ping Lin, G. Vita, S. Attarian, V. Planté-Bordeneuve, M. Mezei, J. Campistol, J. Buades, T. Brannagan, Byoung-Joon Kim, Jeeyoung Oh, Y. Parman, Y. Sekijima, P. Hawkins, S. Solomon, M. Polydefkis, P. Dyck, P. Gandhi, S. Goyal, Jihong Chen, A. Strahs, S. Nochur, M. Sweetser, P. Garg, A. Vaishnaw, J. Gollob, O. Suhr   +35 more
semanticscholar   +1 more source

Technical success, procedural safety, and efficacy of the Silk Vista Baby in the treatment of cerebral aneurysms over a mid-to-long-term follow-up

Frontiers in Neurology
BackgroundLong-term follow-up of cerebral aneurysms treated with the Silk Vista Baby (SVB) flow diverter is lacking. This study aimed to assess the technical success, procedural safety, and efficacy of the SVB (Balt, Montmorency, France) for the ...
Claudio Rodríguez-Fernández, Pedro Ruiz-Garcia, Maria Jesús Garcia-Sanchez, Martiel Manrique-Zegarra, Carlos Toledano-Illán, Jorge Escartin, Miguel Angel Vences, Miguel Angel Vences, Luis Angel Rubio, Alex Luttich, José Manuel Pumar   +10 more
doaj   +1 more source

Recurrent Post-Traumatic Adrenal Bleeding after Transcatheter Arterial Embolization: A Case Report

Journal of the Korean Society of Radiology, 2023
Adrenal gland trauma is uncommon and is diagnosed at an increasing frequency using CT scans. However, owing to the rarity of this injury and its diverse clinical presentations and prognoses, there is no consensus on its management. In this case report,
Hyojoo Kim, Sang Hyun Seo, Hyun Seok Jung   +2 more
doaj   +1 more source

miRNA: A Promising Therapeutic Target in Cancer

International Journal of Molecular Sciences, 2022
microRNAs are small non-coding RNAs that regulate several genes post-transcriptionally by complementarity pairing. Since discovery, they have been reported to be involved in a variety of biological functions and pathologies including cancer.
Amrutha Menon, Noraini Abd-Aziz, Kanwal Khalid, C. Poh, R. Naidu   +4 more
semanticscholar   +1 more source

Support Systems and Limitations in Therapeutic Abortion Care by the Gynecologist-Obstetrician of Public Hospitals in Peru

Revista Brasileira de Ginecologia e Obstetrícia, 2022
Objective To identify the barriers to provide to women and adequately train physicians on therapeutic abortions in public hospitals in Peru. Methods Descriptive cross-sectional survey-based study.
Juan Matzumura, Hugo Gutierrez-Crespo, Enrique Guevara, Luis Meza, Mauricio La Rosa   +4 more
doaj   +1 more source