Results 51 to 60 of about 6,381,108 (341)

Antimicrobial Peptides Demonstrate Activity against Resistant Bacterial Pathogens

open access: yesInfectious Disease Reports, 2023
The antimicrobial resistance crisis is an ongoing major threat to public health safety. Low- and middle-income countries are particularly susceptible to higher fatality rates and the economic impact of antimicrobial resistance (AMR).
Mary Garvey
doaj   +1 more source

Therapeutic ultrasound

open access: yesUltrasound in Medicine & Biology, 1986
Currently the most widely applied use of therapeutic ultrasound in ophthalmology is for the treatment of refractory glaucoma. This new technique is described, histologic changes in experimental animals discussed, and mode of action postulated. The intraocular pressure (IOP) results obtained after treatment of 187 patient eyes are presented, with a ...
D J, Coleman   +6 more
openaire   +2 more sources

Macromolecular therapeutics [PDF]

open access: yesJournal of Controlled Release, 2014
This review covers water-soluble polymer-drug conjugates and macromolecules that possess biological activity without attached low molecular weight drugs. The main design principles of traditional and backbone degradable polymer-drug conjugates as well as the development of a new paradigm in nanomedicines - (low molecular weight) drug-free ...
Jiyuan, Yang, Jindřich, Kopeček
openaire   +2 more sources

Pazopanib Combined With Vincristine and Irinotecan in Relapsed Wilms Tumor: Encouraging Outcomes in a Heavily Pretreated Pediatric Cohort

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background While Wilms tumor (WT) typically has a favorable prognosis, relapsed cases—especially those with high‐risk histology—remain therapeutically challenging after intensive frontline therapy. The combination of vincristine and irinotecan has demonstrated activity in pediatric solid tumors, and pazopanib, a multi‐targeted tyrosine kinase ...
Maria Debora De Pasquale   +6 more
wiley   +1 more source

Therapeutic Phage Display-Derived Single-Domain Antibodies for Pandemic Preparedness

open access: yesAntibodies, 2023
Driven by necessity, the COVID-19 pandemic caused by SARS-CoV-2 has accelerated the development and implementation of new vaccine platforms and other viral therapeutics. Among these is the therapeutic use of antibodies including single-domain antibodies,
Janet M. Daly   +2 more
doaj   +1 more source

Potential Early Risk Biomarkers for Reduced Forced Expiratory Volume in Children Post‐Hematopoietic Cell Transplantation

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT We sought to identify potential early risk biomarkers for lung disease in children post‐allogeneic HCT. Patients with pulmonary function tests 3 months post‐transplant and plasma samples between days 7 and 14 post‐HCT were included. Six of 27 subjects enrolled had reduced forced expiratory volume 1 (FEV1) z scores.
Isabella S. Small   +3 more
wiley   +1 more source

The Role of Extracellular Vesicles in Idiopathic Pulmonary Fibrosis Progression: An Approach on Their Therapeutics Potential

open access: yesCells, 2022
Idiopathic pulmonary fibrosis (IPF) is a fibrosing interstitial lung disease of unknown etiology. Different types of cells are involved in fibrogenesis, which is persistently physical and molecular stimulation, either directly or by interacting with ...
Alma Aurora Ramírez-Hernández   +8 more
doaj   +1 more source

Personality disorder and intellectual disability: the impacts of horticultural therapy within a medium-secure unit [PDF]

open access: yes, 2016
This study was designed to explore the efficacy of a horticultural therapy intervention for the enhancement of subjective health and wellbeing in male service users with a dual diagnosis of personality disorder and intellectual disability in a medium ...
Christie, Mark   +3 more
core   +1 more source

Personalizing the Pediatric Hematology/Oncology Fellowship: Adapting Training for the Next Generation

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT The pediatric hematology‐oncology fellowship training curriculum has not substantially changed since its inception. The first year of training is clinically focused, and the second and third years are devoted to scholarship. However, this current structure leaves many fellows less competitive in the current job market, resulting in ...
Scott C. Borinstein   +3 more
wiley   +1 more source

Hepatobronchial Fistula and Lung Abscess after Transarterial Chemoembolization

open access: yesThe Korean Journal of Gastroenterology, 2017
Transarterial chemoembolization (TACE) is a common treatment modality to locally manage hepatocellular carcinoma. Liver abscess and bile duct injury are common complications of TACE. However, hepatobronchial fistula is a rare complication.
Kwanjoo Lee   +3 more
doaj   +1 more source

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