Results 31 to 40 of about 2,620,997 (289)

Creating New β-Globin-Expressing Lentiviral Vectors by High-Resolution Mapping of Locus Control Region Enhancer Sequences. [PDF]

, 2020
Hematopoietic stem cell gene therapy is a promising approach for treating disorders of the hematopoietic system. Identifying combinations of cis-regulatory elements that do not impede packaging or transduction efficiency when included in lentiviral ...
Aleshe, Bamidele, Ayoub, Paul George, Brown, Devin, Hollis, Roger P, Kohn, Donald B, Kurita, Ryo, Lathrop, Lindsay, Ma, Feiyang, Morgan, Richard A, Nakamura, Yukio, Pellegrini, Matteo, Senadheera, Shantha, Tam, Curtis, Unti, Mildred J, Wong, Ryan L   +14 more
core   +1 more source

Women’s experiences of wearing therapeutic footwear in three European countries [PDF]

, 2010
Background: Therapeutic footwear is recommended for those people with severe foot problems associated with rheumatoid arthritis (RA). However, it is known that many do not wear them.
A Williams, AE Williams, AE Williams, Anita E Williams, Anke Kottink, ARMA (Arthritis and Musculoskeletal Alliance), C Park, Christopher J Nester, Commission Audit, D Whalley, Disabled Living Foundation, FC Arnett, GJ Treharne, HG Gadamer, J Attride-Stirling, J Horder, J Stewart, JJ van Netten, K Aspegren, L Grondal, LML Ong, M Easley, M Fransen, M Janninck, Michael I Ravey, Morey-Gaspar Klapsing, NICE (National Institute for Clinical Excellence), P Bowker, RL Street, S Gutweniger, S Mulhall, S Ryan, SJ Otter, T Koch, V Cooper   +34 more
core   +2 more sources

An integrative in-silico approach for therapeutic target identification in the human pathogen Corynebacterium diphtheriae [PDF]

, 2017
Corynebacterium diphtheriae (Cd) is a Gram-positive human pathogen responsible for diphtheria infection and once regarded for high mortalities worldwide.
Azevedo, Vasco A.C., Barh, Debmalya, Baumbach, Jan, Benevides, Leandro de Jesus, Costa, Daniela Arruda, Ghosh, Preetam, Hassan, Syed Shah, Jamal, Syed Babar, Röttger, Richard, Silva, Artur, Tiwari, Sandeep, Turjanski, Adrián G., Ullah, Asad, Viana, Marcus V.   +13 more
core   +6 more sources

Comprehensive Overview of Ketone Bodies in Cancer Metabolism: Mechanisms and Application

Biomedicines
Reprogramming energy metabolism is pivotal to tumor development. Ketone bodies (KBs), which are generated during lipid metabolism, are fundamental bioactive molecules that can be modulated to satisfy the escalating metabolic needs of cancer cells.
Ziyuan Liang, Lixian Deng, Xiaoying Zhou, Zhe Zhang, Weilin Zhao   +4 more
doaj   +1 more source

Contextualising therapeutic care for child survivors of sexual violence in situations of war: a reflection on theory, context and practice

Intervention Journal of Mental Health and Psychosocial Support in Conflict Affected Areas, 2020
In this article, the author sought to raise awareness of and discuss ways to effectively address contextual challenges faced by mental health workers who provide therapeutic services to child rape survivors in war-affected regions, in general, and in the
Buuma M Maisha
doaj   +1 more source

Innovative therapeutic approach to chemical burns produced by vesicants; an experimental study

Journal of Mind and Medical Sciences, 2022
Vesicants are compounds that cause severe toxic effects on various tissues. Such chemical action causes tissue necrosis, with clinical expression of skin lesions with a burning character and characteristic blisters.
Cristina Anca Secară, Otilia Liudmila Cinteză, Diana Popescu, Claudia Valentina Popa, Camelia Andreea Hîrjeu, Oana Cristina Voinea, Luiza Georgia Șerbănescu, Andreea Marilena Păuna, Mihail Silviu Tudosie   +8 more
doaj   +1 more source

Narrative vignettes and online enquiry in researching therapist accounts of practice with children in schools : an analysis of the methodology [PDF]

, 2013
This article reviews a research methodology which uses a qualitative, narrative approach to online, in-depth analysis of vignettes. The research sought to investigate the ways in which dramatherapists, based in different countries, understood the nature ...
Jones, Phil
core   +2 more sources

Beyond “#endpjparalysis”, tackling sedentary behaviour in health care [PDF]

, 2019
Reducing sedentary behaviour after hospitalization starts with reducing sedentary behaviour whilst in hospital. Although we have eradicated immobilisation as a therapeutic tool due to its potent detrimental effects, it is still in systemic use within ...
Chastin, Sebastien F.M., Dall, Philippa M., Harvey, Juliet A., Mavroeidi, Alexandra, McInally, Lianne, Skelton, Dawn A.   +5 more
core   +4 more sources

Communication and Language Profiles of Children Treated for Posterior Fossa Brain Tumors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cognitive and language deficits are frequently reported sequelae of posterior fossa brain tumors (PFBT). Typically, delayed onset impedes prompt assessment and early intervention. This has devastating implications for quality of life.
Zara Sved, Meghan Hesse, Jennie Cusiter, Annabel Webb, Kimberley Docking   +4 more
wiley   +1 more source

The HIT Network for Children and Adolescents With CNS Tumors Facilitates Improvements of Diagnostic Assessments, Multimodal Treatments, Individual Counseling, and Research in Germany, Austria, and Switzerland

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The HIT network was established in 2000 to create a population‐based structure aiming to improve survival rates and reduce late effects for children with central nervous system (CNS) tumors by conducting comprehensive clinical trials.
Stefan Rutkowski, Michael C. Frühwald, Gudrun Fleischhack, Stephan Tippelt, Pablo Hernáiz‐Driever, Olaf Witt, Astrid Gnekow, Christof Kramm, Matthias Eyrich, Johannes E. A. Wolf, Hermann Müller, Carsten Friedrich, Uwe R. Kordes, Denise Obrecht‐Sturm, Petra Ketteler, Barbara von Zezschwitz, Pascal Johann, Dominik Sturm, Karoline Nemes, Stefan Schönberger, Till Milde, Brigitte Bison, Monika Warmuth‐Metz, Torsten Pietsch, Ulrich Schüller, Arend Koch, David Capper, Martin Hasselblatt, Christian Thomas, Christian Hagel, Stefan M. Pfister, Felix Sahm, David T. W. Jones, Martin U. Schuhmann, Jürgen Krauss, Pedram Emami, Ahmed El Damaty, Rolf D. Kortmann, Rudolf Schwarz, Jürgen Debus, Mechthild Krause, Fabian Pohl, Holger Ottensmeier, Lisa Bußenius, Katja Baust, Andreas Faldum, Cecile Ronckers, Desiree Grabow, Martin Benesch, Thomas Perwein, Karin Dieckmann, Irene Slavc, Johannes Gojo, Nicolas U. Gerber, André O. von Bueren, Katrin Scheinemann, Gabriele Calaminus, Beate Timmermann, Ulrich‐Wilhelm Thomale, Martin Mynarek   +59 more
wiley   +1 more source