Results 11 to 20 of about 1,673,090 (317)

Exploring the contribution of pro-inflammatory cytokines to impaired wound healing in diabetes

open access: yesFrontiers in Immunology, 2023
BackgroundImpaired wound healing is the most common and significant complication of Diabetes. While most other complications of Diabetes have better treatment options, diabetic wounds remain a burden as they can cause pain and suffering in patients ...
S. Nirenjen   +15 more
doaj   +1 more source

PHARMACOGENETICS APPROACH TO THERAPEUTICS [PDF]

open access: yesClinical and Experimental Pharmacology and Physiology, 2006
1. Pharmacogenetics refers to the study of genetically controlled variations in drug response. Functional variants caused by single nucleotide polymorphisms (SNPs) in genes encoding drug-metabolising enzymes, transporters, ion channels and drug receptors have been known to be associated with interindividual and interethnic variation in drug response ...
Seok Hwee, Koo, Edmund Jon Deoon, Lee
openaire   +2 more sources

Autophagic Organelles in DNA Damage Response

open access: yesFrontiers in Cell and Developmental Biology, 2021
Autophagy is an important subcellular event engaged in the maintenance of cellular homeostasis via the degradation of cargo proteins and malfunctioning organelles.
Jeongha Kim   +7 more
doaj   +1 more source

Implications of FBXW7 in Neurodevelopment and Neurodegeneration: Molecular Mechanisms and Therapeutic Potential

open access: yesFrontiers in Cellular Neuroscience, 2021
The ubiquitin-proteasome system (UPS) mediated protein degradation is crucial to maintain quantitive and functional homeostasis of diverse proteins. Balanced cellular protein homeostasis controlled by UPS is fundamental to normal neurological functions ...
Yu Yang   +11 more
doaj   +1 more source

The Functional Deubiquitinating Enzymes in Control of Innate Antiviral Immunity

open access: yesAdvanced Science, 2021
Innate antiviral immunity is the first line of host defense against invading viral pathogens. Immunity activation primarily relies on the recognition of pathogen‐associated molecular patterns (PAMPs) by pattern recognition receptors (PRRs).
Zhi Zong   +4 more
doaj   +1 more source

Combining the Anticancer and Immunomodulatory Effects of Astragalus and Shiitake as an Integrated Therapeutic Approach

open access: yes, 2021
Astragalus root (Huang Qi) and Shiitake mushrooms (Lentinus edodes) are both considered medicinal foods and are frequently used in traditional Chinese medicine due to their anticancer and immunomodulating properties.
Bunu Tamang   +13 more
core   +1 more source

A novel music-based therapeutic approach: the Therapeutic Music Listening [PDF]

open access: yes, 2023
The therapeutic use of music is frequently based on active interventions that directly involve the patient through a sonorous-music interaction with the music therapist.
Alfredo Raglio
core   +1 more source

New Methods for Clinical Proteomics in Allergy

open access: yesAllergology International, 2005
Recent genomic studies have revealed many kinds of genetic polymorphisms. Some genetic polymorphisms have a correlation with allergic phenotypes, however there is only a statistical association without a precise molecular mechanism being demonstrated ...
Zenichiro Kato, Naomi Kondo
doaj   +1 more source

Therapeutic approaches for shankopathies [PDF]

open access: yesDevelopmental Neurobiology, 2013
ABSTRACTDespite recent advances in understanding the molecular mechanisms of autism spectrum disorders (ASD), the current treatments for these disorders are mostly focused on behavioral and educational approaches. The considerable clinical and molecular heterogeneity of ASD present a significant challenge to the development of an effective treatment ...
Wang, Xiaoming   +4 more
openaire   +4 more sources

Inflammatory bowel disease: pathogenesis, diagnosis and current therapeutic approach

open access: yesJournal of Mind and Medical Sciences, 2022
Inflammatory bowel disease is a group of conditions of unknown etiology, represented by Crohn’s disease and ulcerative colitis and characterized by the presence of intestinal wall inflammation. From the first cases described to date, several studies have
Adrian Silaghi   +7 more
doaj   +1 more source

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