Results 11 to 20 of about 1,521,317 (268)

Deubiquitylating Enzymes in Cancer and Immunity

Advanced Science, 2023
Deubiquitylating enzymes (DUBs) maintain relative homeostasis of the cellular ubiquitome by removing the post‐translational modification ubiquitin moiety from substrates.
Jiang Ren, Peng Yu, Sijia Liu, Ran Li, Xin Niu, Yan Chen, Zhenyu Zhang, Fangfang Zhou, Long Zhang   +8 more
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Antioxidant effect of grape seed extract corrects experimental autoimmune encephalomyelitis behavioral dysfunctions, demyelination, and glial activation

Frontiers in Immunology, 2022
Background and purposeMultiple sclerosis (MS), a multifactorial autoimmune disease of the central nervous system (CNS), is characterized by demyelination and chronic inflammation, as well as axonal and neuronal loss.
Maha Mabrouk, Maha Mabrouk, Maha Mabrouk, Maha Mabrouk, Mohamed El Ayed, Mohamed El Ayed, Amélie Démosthènes, Amélie Démosthènes, Youssef Aissouni, Youssef Aissouni, Ezzedine Aouani, Ezzedine Aouani, Laurence Daulhac-Terrail, Laurence Daulhac-Terrail, Meherzia Mokni, Meherzia Mokni, Mélina Bégou, Mélina Bégou   +17 more
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Approach to the patient with metabolic syndrome in general medicine [PDF]

Opšta Medicina, 2017
Introduction: Metabolic syndrome (MS) is a collection of metabolic disorders that increase the risk of developing diabetes and cardiovascular disease and is a serious public health problem. Objective: 1.
Petrov-Kiurski Miloranka Đ.
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Exploring the contribution of pro-inflammatory cytokines to impaired wound healing in diabetes

Frontiers in Immunology, 2023
BackgroundImpaired wound healing is the most common and significant complication of Diabetes. While most other complications of Diabetes have better treatment options, diabetic wounds remain a burden as they can cause pain and suffering in patients ...
S. Nirenjen, J. Narayanan, T. Tamilanban, Vetriselvan Subramaniyan, Vetriselvan Subramaniyan, V. Chitra, Neeraj Kumar Fuloria, Ling Shing Wong, Gobinath Ramachawolran, Mahendran Sekar, Gaurav Gupta, Gaurav Gupta, Shivkanya Fuloria, Suresh V. Chinni, Suresh V. Chinni, Siddharthan Selvaraj   +15 more
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Therapeutic approaches for shankopathies [PDF]

Developmental Neurobiology, 2013
ABSTRACTDespite recent advances in understanding the molecular mechanisms of autism spectrum disorders (ASD), the current treatments for these disorders are mostly focused on behavioral and educational approaches. The considerable clinical and molecular heterogeneity of ASD present a significant challenge to the development of an effective treatment ...
Wang, Xiaoming, Bey, Alexandra L, Chung, Leeyup, Krystal, Andrew D, Jiang, Yong‐Hui   +4 more
openaire   +4 more sources

Inflammatory bowel disease: pathogenesis, diagnosis and current therapeutic approach

Journal of Mind and Medical Sciences, 2022
Inflammatory bowel disease is a group of conditions of unknown etiology, represented by Crohn’s disease and ulcerative colitis and characterized by the presence of intestinal wall inflammation. From the first cases described to date, several studies have
Adrian Silaghi, Vlad Denis Constantin, Bogdan Socea, Petrișor Banu, Vladimir Sandu, Liliana Florina Andronache, Anca Silvia Dumitriu, Stana Paunica   +7 more
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Reaching in reality and virtual reality: a comparison of movement kinematics in healthy subjects and in adults with hemiparesis

Journal of NeuroEngineering and Rehabilitation, 2004
Background Virtual reality (VR) is an innovative tool for sensorimotor rehabilitation increasingly being employed in clinical and community settings. Despite the growing interest in VR, few studies have determined the validity of movements made in VR ...
Feldman Anatol G, Viau Antonin, McFadyen Bradford J, Levin Mindy F   +3 more
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Investigation of DHA-Induced Regulation of Redox Homeostasis in Retinal Pigment Epithelium Cells through the Combination of Metabolic Imaging and Molecular Biology

Antioxidants, 2022
Diabetes-induced oxidative stress leads to the onset of vascular complications, which are major causes of disability and death in diabetic patients. Among these, diabetic retinopathy (DR) often arises from functional alterations of the blood-retinal ...
Giada Bianchetti, Maria Elisabetta Clementi, Beatrice Sampaolese, Cassandra Serantoni, Alessio Abeltino, Marco De Spirito, Shlomo Sasson, Giuseppe Maulucci   +7 more
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The relationship between ferroptosis and respiratory infectious diseases: a novel landscape for therapeutic approach

Frontiers in Immunology
Respiratory infectious diseases, particularly those caused by respiratory viruses, have the potential to lead to global pandemics, thereby posing significant threats to public and human health.
Longyan Hong, Longyan Hong, Xiangyu Chen, Xiangyu Chen, Yiming Liu, Yiming Liu, Hao Liang, Yinghui Zhao, Yinghui Zhao, Pengbo Guo, Pengbo Guo   +10 more
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Case Report: Misdiagnosis of Maturity-Onset Diabetes of the Young as type 1, type 2 or gestational diabetes: insights from a Latin American tertiary center

Frontiers in Medicine
BackgroundMaturity-Onset Diabetes of the Young (MODY) comprises monogenic, non-syndromic forms of diabetes inherited in an autosomal dominant pattern.
Rossana Ruiz-Urbaez, David Males-Maldonado, Mariela Viviana Villagómez-Estrada, Carlos Reyes-Silva, Jorge Salazar-Vega, Gabriela Jaramillo-Koupermann, Diana Sosa-Copa, Enrique Gea-Izquierdo, Enrique Gea-Izquierdo, Enrique Gea-Izquierdo   +9 more
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