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Solution-focused approaches in adult mental health research: A conceptual literature review and narrative synthesis

open access: yesFrontiers in Psychiatry, 2023
Solution-focused approaches are one approach to treatment used in a wide variety of settings in modern mental healthcare services. As yet, there has been no overall synthesis of how this approach is understood in the adult mental health literature.
Lauren Jerome   +4 more
doaj   +1 more source

Cardiac cellular diversity and functionality in cardiac repair by single-cell transcriptomics

open access: yesFrontiers in Cardiovascular Medicine, 2023
Cardiac repair after myocardial infarction (MI) is orchestrated by multiple intrinsic mechanisms in the heart. Identifying cardiac cell heterogeneity and its effect on processes that mediate the ischemic myocardium repair may be key to developing novel ...
Wei Chen   +10 more
doaj   +1 more source

Extracellular Vesicles in Multiple Sclerosis: Role in the Pathogenesis and Potential Usefulness as Biomarkers and Therapeutic Tools

open access: yesCells, 2021
Although extracellular vesicles (EVs) were initially relegated to a waste disposal role, nowadays, they have gained multiple fundamental functions working as messengers in intercellular communication as well as exerting active roles in physiological and ...
Marianna D’Anca   +5 more
doaj   +1 more source

Autophagic Organelles in DNA Damage Response

open access: yesFrontiers in Cell and Developmental Biology, 2021
Autophagy is an important subcellular event engaged in the maintenance of cellular homeostasis via the degradation of cargo proteins and malfunctioning organelles.
Jeongha Kim   +7 more
doaj   +1 more source

Confusion of Therapeutic Approaches [PDF]

open access: yesDeutsches Ärzteblatt international, 2014
Schlitt et al. in their review article focused on cardiotoxic oncological treatments (1). Adequate management of adverse effects of cardiotoxic treatments ensures optimal results of oncological treatment. In the article by Schlitt et al., an algorithm was proposed for monitoring, prevention, and treatment in the context of cardiotoxicity, including the
Ivanyi, Philipp   +2 more
openaire   +2 more sources

Implications of FBXW7 in Neurodevelopment and Neurodegeneration: Molecular Mechanisms and Therapeutic Potential

open access: yesFrontiers in Cellular Neuroscience, 2021
The ubiquitin-proteasome system (UPS) mediated protein degradation is crucial to maintain quantitive and functional homeostasis of diverse proteins. Balanced cellular protein homeostasis controlled by UPS is fundamental to normal neurological functions ...
Yu Yang   +11 more
doaj   +1 more source

The Functional Deubiquitinating Enzymes in Control of Innate Antiviral Immunity

open access: yesAdvanced Science, 2021
Innate antiviral immunity is the first line of host defense against invading viral pathogens. Immunity activation primarily relies on the recognition of pathogen‐associated molecular patterns (PAMPs) by pattern recognition receptors (PRRs).
Zhi Zong   +4 more
doaj   +1 more source

PHARMACOGENETICS APPROACH TO THERAPEUTICS [PDF]

open access: yesClinical and Experimental Pharmacology and Physiology, 2006
1. Pharmacogenetics refers to the study of genetically controlled variations in drug response. Functional variants caused by single nucleotide polymorphisms (SNPs) in genes encoding drug-metabolising enzymes, transporters, ion channels and drug receptors have been known to be associated with interindividual and interethnic variation in drug response ...
Seok Hwee, Koo, Edmund Jon Deoon, Lee
openaire   +2 more sources

Experiences of student nurses on role modelling of a therapeutic approach by registered nurses: Recommendations for improvement

open access: yesCurationis, 2021
Background: A therapeutic approach involves portraying the attributes of being polite towards fellow human beings and patients, respecting them irrespective of their circumstances and having sympathy and compassion for them.
Esther A. Mpangane   +2 more
doaj   +1 more source

Managing Fetal Ovarian Cysts: Clinical Experience with a Rare Disorder

open access: yesMedicina, 2023
Background and Objectives: Fetal ovarian cysts (FOCs) are a very rare pathology that can be associated with maternal–fetal and neonatal complications. The aim of this study was to assess the influence of ultrasound characteristics on FOC evolution and ...
Alina-Sinziana Melinte-Popescu   +9 more
doaj   +1 more source

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