Results 21 to 30 of about 1,673,090 (317)

Investigation of DHA-Induced Regulation of Redox Homeostasis in Retinal Pigment Epithelium Cells through the Combination of Metabolic Imaging and Molecular Biology

Antioxidants, 2022
Diabetes-induced oxidative stress leads to the onset of vascular complications, which are major causes of disability and death in diabetic patients. Among these, diabetic retinopathy (DR) often arises from functional alterations of the blood-retinal ...
Giada Bianchetti, Maria Elisabetta Clementi, Beatrice Sampaolese, Cassandra Serantoni, Alessio Abeltino, Marco De Spirito, Shlomo Sasson, Giuseppe Maulucci   +7 more
doaj   +1 more source

Bruton’s tyrosine kinase as a promising therapeutic target for multiple sclerosis

, 2023
347359Introduction: Multiple sclerosis (MS) is the most common demyelinating disease of the central nervous system (CNS). Although there are several disease-modifying therapies that can effectively manage MS relapses, the treatment of chronic progressive
Dybowski, Sarah, Sarah Dybowski, Weber, Martin S., Darius Saberi, Geladaris, Anastasia, Weber, Martin, Anastasia Geladaris, Saberi, Darius, Martin S. Weber   +8 more
core   +1 more source

The relationship between ferroptosis and respiratory infectious diseases: a novel landscape for therapeutic approach

Frontiers in Immunology
Respiratory infectious diseases, particularly those caused by respiratory viruses, have the potential to lead to global pandemics, thereby posing significant threats to public and human health.
Longyan Hong, Longyan Hong, Xiangyu Chen, Xiangyu Chen, Yiming Liu, Yiming Liu, Hao Liang, Yinghui Zhao, Yinghui Zhao, Pengbo Guo, Pengbo Guo   +10 more
doaj   +1 more source

Case Report: Misdiagnosis of Maturity-Onset Diabetes of the Young as type 1, type 2 or gestational diabetes: insights from a Latin American tertiary center

Frontiers in Medicine
BackgroundMaturity-Onset Diabetes of the Young (MODY) comprises monogenic, non-syndromic forms of diabetes inherited in an autosomal dominant pattern.
Rossana Ruiz-Urbaez, David Males-Maldonado, Mariela Viviana Villagómez-Estrada, Carlos Reyes-Silva, Jorge Salazar-Vega, Gabriela Jaramillo-Koupermann, Diana Sosa-Copa, Enrique Gea-Izquierdo, Enrique Gea-Izquierdo, Enrique Gea-Izquierdo   +9 more
doaj   +1 more source

Molecular treatment options for patients carrying KIAA0586/TALPID3 variants

Molecular Therapy: Nucleic Acids
Variants in KIAA0586/TALPID3 are associated with the ciliopathy Joubert syndrome (JS), which is a genetically heterogeneous disorder. Mutations in more than 40 different genes were associated with JS, genes that are relevant to ciliary assembly ...
Jacqueline E. Taudien, Sebastian Swirski, Maike Möller, Christoph Jüschke, Marta Owczarek-Lipska, G. Christoph Korenke, John Neidhardt   +6 more
doaj   +1 more source

Contextualising therapeutic care for child survivors of sexual violence in situations of war: a reflection on theory, context and practice

Intervention Journal of Mental Health and Psychosocial Support in Conflict Affected Areas, 2020
In this article, the author sought to raise awareness of and discuss ways to effectively address contextual challenges faced by mental health workers who provide therapeutic services to child rape survivors in war-affected regions, in general, and in the
Buuma M Maisha
doaj   +1 more source

Innovative therapeutic approach to chemical burns produced by vesicants; an experimental study

Journal of Mind and Medical Sciences, 2022
Vesicants are compounds that cause severe toxic effects on various tissues. Such chemical action causes tissue necrosis, with clinical expression of skin lesions with a burning character and characteristic blisters.
Cristina Anca Secară, Otilia Liudmila Cinteză, Diana Popescu, Claudia Valentina Popa, Camelia Andreea Hîrjeu, Oana Cristina Voinea, Luiza Georgia Șerbănescu, Andreea Marilena Păuna, Mihail Silviu Tudosie   +8 more
doaj   +1 more source

A therapeutic approach for ASD: method and outcome of the DERBBI – Developmental, Emotional Regulation and Body-Based Intervention

International Journal of Psychoanalysis and Education, 2020
Autism spectrum disorder (ASD) is a neurodevelopmental disorder displaying individual impairments in social interaction, communication skills, interest and behaviours.
Magda Di Renzo, Elena Vanadia, Massimiliano Petrillo, Davide Trapolino, Lidia Racinaro, Monica Rea, Federico Bianchi di Castelbianco   +6 more
doaj  

Carcinomas and Carcinoid Tumors of the Lungs and Bronchi in Children and Adolescents: The EXPeRT Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Primary lung carcinomas and bronchial carcinoid tumors (BC) are very rare malignancies in childhood. While typical BC and mucoepidermoid carcinomas are mostly low‐grade, localized tumors with a more favorable prognosis than in adults, necessitating avoidance of overtreatment, adenocarcinomas of the lung are often diagnosed at advanced disease ...
Michael Abele, Calogero Virgone, Michaela Kuhlen, Sabine Irtan, Yves Reguerre, Malgorzata Krawczyk, Ewa Bien, Tal Ben‐Ami, Maja Cesen, Ricardo Lopez‐Almaraz, Andrea Ferrari, Gianni Bisogno, Dominik T. Schneider, Abbas Agaimy, Constantin Lapa, Hubert Ducou le Pointe, Rainer Claus, Catherine Daniel, Ines B. Brecht, Daniel Orbach   +19 more
wiley   +1 more source

The therapeutic effect of traditional Chinese medicine on breast cancer through modulation of the Wnt/β-catenin signaling pathway

Frontiers in Pharmacology
Breast cancer, the most prevalent malignant tumor among women globally, is significantly influenced by the Wnt/β-catenin signaling pathway, which plays a crucial role in its initiation and progression.
Hongkun Li, Jiawei Li, Yifan Zhang, Chengcheng Zhao, Jun Ge, Yujiao Sun, Hui Fu, Yingpeng Li   +7 more
doaj   +1 more source