Results 21 to 30 of about 32,878,841 (350)

Nanotherapeutic and Stem Cell Therapeutic Strategies in Neurodegenerative Diseases: A Promising Therapeutic Approach

International Journal of Nanomedicine, 2023
Neurodegeneration is characterized by progressive, disabling, and incurable neurological disorders with the massive loss of specific neurons. As one of the most promising potential therapeutic strategies for neurodegenerative diseases, stem cell therapy ...
Min Wei, Zhao-Fei Yang, Song Li, W. Le
semanticscholar   +1 more source

Antisense oligonucleotide silencing of FUS expression as a therapeutic approach in amyotrophic lateral sclerosis

Nature Medicine, 2022
Fused in sarcoma (FUS) is an RNA-binding protein that is genetically and pathologically associated with rare and aggressive forms of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).
Vlad A. Korben, Alex K. Lyashchenko, Beatriz Blanco-Redondo, Paayman Jafar-nejad, N. Shneider   +4 more
semanticscholar   +1 more source

The Main Changes in Pregnancy—Therapeutic Approach to Musculoskeletal Pain

Medicina, 2022
Background and Objectives: During pregnancy, women undergo various physiological and anatomical changes that are accentuated as the pregnancy progresses, but return to their previous state a few weeks/months after the pregnancy.
Felicia Fiat, P. Mergheş, A. Scurtu, Bogdan Almajan Guta, C. Dehelean, N. Varan, E. Bernad   +6 more
semanticscholar   +1 more source

Metabolomics and Network Pharmacology in the Exploration of the Multi-Targeted Therapeutic Approach of Traditional Medicinal Plants

Plants, 2022
Metabolomic is generally characterized as a comprehensive and the most copious analytical technique for the identification of targeted and untargeted metabolite diversity in a biological system.
B. Sharma, Dinesh Yadav
semanticscholar   +1 more source

Mitochondrial transfer/transplantation: an emerging therapeutic approach for multiple diseases

Cell & Bioscience, 2022
Mitochondria play a pivotal role in energy generation and cellular physiological processes. These organelles are highly dynamic, constantly changing their morphology, cellular location, and distribution in response to cellular stress.
Zong-gang Liu, Yi Sun, Z. Qi, Lu Cao, S. Ding   +4 more
semanticscholar   +1 more source

Current Understanding of the Physiopathology, Diagnosis and Therapeutic Approach to Alzheimer’s Disease

Biomedicines, 2021
Alzheimer’s disease (AD) is the most common cause of dementia. It is characterized by cognitive decline and progressive memory loss. The aim of this review was to update the state of knowledge on the pathophysiological mechanisms, diagnostic methods and ...
V. García-Morales, Anabel Gónzalez-Acedo, L. Melguizo-Rodríguez, Teresa Pardo-Moreno, V. Costela-Ruiz, Maria Montiel-Troya, Juan José Ramos-Rodríguez   +6 more
semanticscholar   +1 more source

Ferroptosis inducers are a novel therapeutic approach for advanced prostate cancer

Cancer Research, 2021
These findings reveal that induction of ferroptosis is a new therapeutic strategy for advanced prostate cancer as a monotherapy and in combination with second-generation antiandrogens.
Ali Ghoochani, En-Chi Hsu, Merve Aslan, Meghan A. Rice, Holly M. Nguyen, J. Brooks, E. Corey, R. Paulmurugan, Tanya Stoyanova   +8 more
semanticscholar   +1 more source

Immunotherapy: an alternative promising therapeutic approach against cancers

Molecular Biology Reports, 2022
The immune system interacts with cancer cells in multiple intricate ways that can shield the host against hyper-proliferation but can also contribute to malignancy.
Sneh Lata Gupta, S. Basu, V. Soni, R. Jaiswal   +3 more
semanticscholar   +1 more source

Targeting neuroinflammation as a preventive and therapeutic approach for perioperative neurocognitive disorders

Journal of Neuroinflammation, 2022
Perioperative neurocognitive disorders (PND) is a common postoperative complication associated with regional or general anesthesia and surgery. Growing evidence in both patient and animal models of PND suggested that neuroinflammation plays a critical ...
Chun Cheng, H. Wan, Peilin Cong, Xin-Wei Huang, Tingmei Wu, Meng-Fan He, Q. Zhang, Li-Ze Xiong, Li Tian   +8 more
semanticscholar   +1 more source

An update of current therapeutic approach for Intervertebral Disc Degeneration: A review article

Annals of Medicine and Surgery, 2022
Intervertebral disc degeneration is a natural process of aging. It can cause physical, psychological, and socioeconomic impact due to the decreasing function of the spine and pain manifestation. Conservative and surgical treatment to correct symptoms and
Romaniyanto, F. Mahyudin, C. R. Sigit Prakoeswa, H. Notobroto, D. Tinduh, Ryan Ausrin, F. Rantam, H. Suroto, D. Utomo, S. Rhatomy   +9 more
semanticscholar   +1 more source