Results 41 to 50 of about 18,121,732 (293)

A Systematic Review of Therapeutic Approaches Used in Experimental Models of Interstitial Cystitis/Bladder Pain Syndrome

Biomedicines, 2021
Interstitial cystitis/bladder pain syndrome (IC/BPS) is a multifactorial, chronic bladder disorder with limited therapeutic options currently available. The present review provides an extensive overview of therapeutic approaches used in in vitro, ex vivo,
Tadeja Kuret, Dominika Peskar, Andreja Erman, Peter Veranič   +3 more
doaj   +1 more source

Bacterial Biofilm in Chronic Wounds and Possible Therapeutic Approaches

Biology
Simple Summary Chronic wounds consist of those injuries that have failed to complete the healing process. This type of wound is frequently infected by pathogens and represents a challenging medical situation, a substantial cause of health problems, and a
Ilaria Cavallo, Francesca Sivori, Arianna Mastrofrancesco, E. Abril, M. Pontone, E. D. Di Domenico, F. Pimpinelli   +6 more
semanticscholar   +1 more source

Strategizing Drug Therapies in Pulmonary Hypertension for Improved Outcomes

Pharmaceuticals, 2022
Pulmonary hypertension (PH) is characterized by a resting mean pulmonary artery pressure (PAP) of 20 mmHg or more and is a disease of multiple etiologies.
Taylor Beckmann, Patrisha Shelley, Darshan Patel, Mounica Vorla, Dinesh K. Kalra   +4 more
doaj   +1 more source

Current advancements in therapeutic approaches in orthopedic surgery: a review of recent trends

Frontiers in Bioengineering and Biotechnology
Recent advancements in orthopedic surgery have greatly improved the management of musculoskeletal disorders and injuries. This review discusses the latest therapeutic approaches that have emerged in orthopedics.
Wenqing Liang, Chao Zhou, Juqin Bai, Hongwei Zhang, Bo Jiang, Jiangwei Wang, Lifeng Fu, Hengguo Long, Xiaogang Huang, Jiayi Zhao, Haibing Zhu   +10 more
semanticscholar   +1 more source

Cutaneous Squamous Cell Carcinoma: From Pathophysiology to Novel Therapeutic Approaches

Biomedicines, 2021
Cutaneous squamous cell carcinoma (cSCC), a non-melanoma skin cancer, is a keratinocyte carcinoma representing one of the most common cancers with an increasing incidence. cSCC could be in situ (e.g., Bowen’s disease) or an invasive form.
L. Fania, D. Didona, F. D. Di Pietro, S. Verkhovskaia, R. Morese, G. Paolino, M. Donati, Francesca Ricci, Valeria Coco, Francesco Ricci, E. Candi, D. Abeni, E. Dellambra   +12 more
semanticscholar   +1 more source

Update on therapeutic approaches for invasive fungal infections in adults

Therapeutic Advances in Infectious Disease
Invasive fungal infections are increasingly encountered with the expansion of iatrogenic immunosuppression, including not only solid organ and hematopoietic stem cell transplant recipients but also patients with malignancies or autoimmune diseases ...
Catherine-Audrey Boutin, M. Luong
semanticscholar   +1 more source

Pathophysiology and Therapeutic Approaches to Acute Decompensated Heart Failure

Circulation Research, 2021
Supplemental Digital Content is available in the text. Acute decompensated heart failure (ADHF) is one of the leading admission diagnoses worldwide, yet it is an entity with incompletely understood pathophysiology and limited therapeutic options ...
Joyce N. Njoroge, J. Teerlink
semanticscholar   +1 more source

Communication and Language Profiles of Children Treated for Posterior Fossa Brain Tumors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cognitive and language deficits are frequently reported sequelae of posterior fossa brain tumors (PFBT). Typically, delayed onset impedes prompt assessment and early intervention. This has devastating implications for quality of life.
Zara Sved, Meghan Hesse, Jennie Cusiter, Annabel Webb, Kimberley Docking   +4 more
wiley   +1 more source

Identification of a culturable fungal species and endosymbiotic bacteria in saliva of Aedes aegypti and Culex pipiens and their impact on arbovirus infection in vitro

Parasites & Vectors
Background Mosquito saliva plays a key role in arbovirus transmission and pathogenesis. It was shown that saliva contains several molecules that are essential for blood feeding.
Lanjiao Wang, Laure Remue, Nikki Adriaens, Alina Soto, Sam Verwimp, Joyce van Bree, Katrien Trappeniers, Leen Delang   +7 more
doaj   +1 more source

Metabolism-based approaches for autosomal dominant polycystic kidney disease

Frontiers in Molecular Biosciences, 2023
Autosomal Dominant Polycystic Kidney Disease (ADPKD) leads to end stage kidney disease (ESKD) through the development and expansion of multiple cysts throughout the kidney parenchyma.
Ivona Bakaj, Alessandro Pocai
doaj   +1 more source