Results 51 to 60 of about 1,016,867 (303)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The growth of recovery capital in clients of recovery residences in Florida, USA: a quantitative pilot study of changes in REC-CAP profile scores

Substance Abuse Treatment, Prevention, and Policy, 2022
Background There is a growing evidence base around predictors of retention and completion in a range of recovery residence models, particularly Oxford Houses and Sober Living Houses, and recovery housing is recognized as a clearly evidenced area of ...
Sofia Härd, David Best, Arun Sondhi, John Lehman, Richard Riccardi   +4 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Understanding of research, genetics and genetic research in a rapid ethical assessment in north west Cameroon [PDF]

, 2015
BACKGROUND There is limited assessment of whether research participants in low-income settings are afforded a full understanding of the meaning of medical research. There may also be particular issues with the understanding of genetic research.
Bhutta, Doris N. Nyoh, Gail Davey, James D. Millard, Jonas A. Kengne-Ouafo, Mandava, Melanie J. Newport, Mfutso-Bengo, Nicholas Tendongfor, Peter A. Enyong, Samuel Wanji, Theobald M. Nji, William F. Tantoh   +12 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Therapeutic Community as a Method of Group-Work with Homeless

Paedagogia Christiana, 2014
The article presents basic theoretical assumptions that would justify the legitimacy of usage of the therapeutic community method in the work with the homeless. The Homeless, as those excluded from society, often show a minimalist attitude by reluctantly
Krzysztof Juliusz Pilarz
doaj   +1 more source

Personality disorder not otherwise specified heterogeneity and its implication in psychiatric residential treatment

European Psychiatry, 2021
Introduction Villa Ratti is a therapeutic community dedicated to the treatment of Personality Disorder with a particular focus on Borderline Personality Disorder (BPD), but this diagnosis may manifest in very different clinical conditions (Bayer ...
L. Bailo, P. Vimercati, M. Caslini, S. Damiano, E. Pellegrini   +4 more
doaj   +1 more source

Cognitive Analytic Therapy in People with Learning Disability: An investigation into the common reciprocal roles found within this client group [PDF]

, 2005
Developments over the last twenty years have shown that, contrary to previous opinion, people with learning disabilities can benefit from psychotherapy (Sinason 1992; Kroese, Dagnan & Loumidia, 1997). Cognitive Analytic Therapy (CAT) has been adapted for
A Trzcińska, A Trzcińska, B Kłos, C García-Recio, CJ Batty, CJ Batty, CJ Horowitz, E Friedman, E Friedman, J Jastrzȩbski, N Barnea, O Meirav   +11 more
core   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Risk factors for mortality among kidney transplant recipients with COVID-19 in Saudi Arabia: a case-control study

BMC Infectious Diseases
Background The COVID-19 pandemic, caused by the novel coronavirus SARS-CoV-2, has profoundly impacted global health, leading to over 74 million confirmed cases and 1.67 million deaths by December 2020. In Saudi Arabia, extensive measures were implemented
Dema A. Alissa, Rawan Almasuood, Baraa Alghalyini, Hala Tamim, Mohammed Alaa Raslan, Abdul Rehman Zia Zaidi, Bader Abou Shaar, Mhd Malek Al Masri, Adnan Abdul Karim, Wejdan Aburas, Waled Aburas, Ahmed H. Al-jedai, Reem S. Almaghrabi   +12 more
doaj   +1 more source