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Cancer Chemotherapy: The Case for Therapeutic Drug Monitoring.

Therapeutic Drug Monitoring, 2020
The selection of an appropriate therapy and dosing regimen is a significant challenge in the treatment of cancer. Although there are recommended standardized chemotherapy protocols for some types of cancer, protocol changes usually only occur after large
Claire E. Knezevic, W. Clarke
semanticscholar   +1 more source

Therapeutic drug monitoring

Acta Neuropsychiatrica, 1999
SUMMARYThe cytochrome P450 iso-enzyme system plays a key role in the biotransformation of many drugs, including psychotropics. Its activity is determined by both genetic and environmental factors. The most important iso-enzymes for psychiatry in general are P450 IID6, 3A4 and 1A2.
J B, Noten   +3 more
openaire   +2 more sources

Therapeutic drug monitoring of antiepileptic drugs: current status and future prospects

Expert Opinion on Drug Metabolism & Toxicology, 2020
Introduction: Antiepileptic drugs (AEDs) are the cornerstone of treatment of patients with epilepsy, and there are presently 27 licensed AEDs making AEDs among the most common medications for which therapeutic drug monitoring (TDM) is performed.
Cecilie Johannessen Landmark   +2 more
semanticscholar   +1 more source

Therapeutic drug monitoring

2014
Only a small fraction of drugs (approximately 50) out of over 3,000 prescription drugs require therapeutic drug monitoring; usually 20–30 drugs are routinely monitored in most hospital laboratories. Immunoassays are available for monitoring 26 drugs, while for monitoring less frequently ordered drugs, chromatographic techniques must be used.
Amitava Dasgupta, Amer Wahed
openaire   +3 more sources

Blood Levels to Optimize Antipsychotic Treatment in Clinical Practice: A Joint Consensus Statement of the American Society of Clinical Psychopharmacology and the Therapeutic Drug Monitoring Task Force of the Arbeitsgemeinschaft für Neuropsychopharmakologie und Pharmakopsychiatrie.

Journal of Clinical Psychiatry, 2020
OBJECTIVE The quantification of antipsychotic levels in blood, also known as therapeutic drug monitoring (TDM), is a potentially useful tool of modern personalized therapy that can be applied to augment antipsychotic use and dosing decisions.
G. Schoretsanitis   +18 more
semanticscholar   +1 more source

Evidence-based Guideline for Therapeutic Drug Monitoring of Vancomycin: 2020 Update by the Division of Therapeutic Drug Monitoring, Chinese Pharmacological Society.

Clinical Infectious Diseases, 2020
BACKGROUND Clinical practice guidelines or recommendations often require timely and regular updating as new evidence emerges, because this can alter the risk-benefit trade-off.
N. He   +53 more
semanticscholar   +1 more source

TDM: Therapeutic Drug Measuring or Therapeutic Drug Monitoring?

Therapeutic Drug Monitoring, 2005
The third round of the International Interlaboratory Quality Control Program for Therapeutic Drug Monitoring in HIV infection (QC-program) consisted of the analysis not only of plasma samples but also of patient cases. The case was composed of different topics related to the therapeutic drug monitoring of antiretroviral drugs.
Droste, J.A.H.   +3 more
openaire   +4 more sources

Therapeutic Drug Monitoring of Long-Acting Injectable Antipsychotic Drugs.

Therapeutic Drug Monitoring, 2020
PURPOSE The use of therapeutic drug monitoring (TDM) to guide treatment with long-acting injectable (LAI) antipsychotics, which are increasingly prescribed, remains a matter of debate.
G. Schoretsanitis   +15 more
semanticscholar   +1 more source

Therapeutic Drug Monitoring of Targeted Anticancer Protein Kinase Inhibitors in Routine Clinical Use: A Critical Review.

Therapeutic Drug Monitoring, 2020
PURPOSE Therapeutic response to oral targeted anticancer protein kinase inhibitors (PKIs) varies widely between patients, with insufficient efficacy of some of them and unacceptable adverse reactions of others.
E. Cardoso   +7 more
semanticscholar   +1 more source

Therapeutic Drug Monitoring of Lamotrigine

Annals of Pharmacotherapy, 2002
OBJECTIVE: To evaluate the usefulness of routine monitoring of serum lamotrigine concentration. DATA SOURCE: Literature was accessed through MEDLINE (1990–January 2001). Key search terms included lamotrigine, pharmacokinetics, and epilepsy. DATA SYNTHESIS: A decision-making algorithm was used to evaluate the clinical evidence to support or refute the ...
Elaine Chong, L. Lee Dupuis
openaire   +3 more sources

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